Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction

Kurzanzeige
dc.contributor.authorSpiteller, Dieter
dc.contributor.authorSpiteller, Gerharddeu
dc.date.accessioned2011-10-20T11:53:25Zdeu
dc.date.available2011-10-20T11:53:25Zdeu
dc.date.issued2000
dc.description.abstractThe oxidation of low-density lipoprotein (LDL) in vitro was studied by a combination of solid-phase microextraction and GC/MS. 2-trans,4-cis-2,4-Decadienal, which is strongly toxic in vitro, was detected as the early oxidation product. This compound is degraded further to hexanal and (by cyclization of 4-hydroxy-2-nonenal) to 2-pentylfuran.eng
dc.description.versionpublished
dc.identifier.citationPubl. in: Angewandte Chemie / International edition : a journal of the Gesellschaft Deutscher Chemiker ; 39 (2000), 3. - S. 583-585deu
dc.identifier.doi10.1002/(SICI)1521-3773(20000204)39:3<583::AID-ANIE583>3.0.CO;2-Odeu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/15586
dc.language.isoengdeu
dc.legacy.dateIssued2011-10-20deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectaldehydesdeu
dc.subjectlipidsdeu
dc.subjectlipoproteinsdeu
dc.subjectoxygenationsdeu
dc.subject.ddc570deu
dc.titleIdentification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextractioneng
dc.typeJOURNAL_ARTICLEdeu
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  title={Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction},
  number={3},
  volume={39},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={583--585},
  author={Spiteller, Dieter and Spiteller, Gerhard}
}
kops.citation.iso690SPITELLER, Dieter, Gerhard SPITELLER, 2000. Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction. In: Angewandte Chemie International Edition. 2000, 39(3), pp. 583-585. ISSN 1433-7851. Available under: doi: 10.1002/(SICI)1521-3773(20000204)39:3<583::AID-ANIE583>3.0.CO;2-Odeu
kops.citation.iso690SPITELLER, Dieter, Gerhard SPITELLER, 2000. Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction. In: Angewandte Chemie International Edition. 2000, 39(3), pp. 583-585. ISSN 1433-7851. Available under: doi: 10.1002/(SICI)1521-3773(20000204)39:3<583::AID-ANIE583>3.0.CO;2-Oeng
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