Facile synthesis of fluorinated purines and thiapurines
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Datum
2007
Autor:innen
Iaroshenko, Viktor O.
Volochnyuk, Dmitriy M.
Vovk, Mikhail V.
Boiko, Vyacheslav J.
Rusanov, Eduard B.
Tolmachev, Andrei A.
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Synthesis: journal of synthetic organic chemistry. 2007, 2007(21), pp. 3309-3318. ISSN 0039-7881. eISSN 1437-210X. Available under: doi: 10.1055/s-2007-990843
Zusammenfassung
The reaction of 2-(dialkylamino)-1,3-thiazol-4-amines and 1,2-dimethyl-IH-imidazol-5-amine with aryl isocyanates, alpha-chloroalkyl isocyanates, N-(alkoxycarbonyl)imidoyl chlorides and 2,4,6-tris(trifluoromethyl)-1,3,5-triazine leads to thiapurines and purines containing trifluoromethyl groups in the 2- and 6-positions of the pyrimidine ring.
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540 Chemie
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imidazole, thiazole, pyrimidine, isocyanate, annulation
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IAROSHENKO, Viktor O., Dmitriy M. VOLOCHNYUK, Yan WANG, Mikhail V. VOVK, Vyacheslav J. BOIKO, Eduard B. RUSANOV, Ulrich GROTH, Andrei A. TOLMACHEV, 2007. Facile synthesis of fluorinated purines and thiapurines. In: Synthesis: journal of synthetic organic chemistry. 2007, 2007(21), pp. 3309-3318. ISSN 0039-7881. eISSN 1437-210X. Available under: doi: 10.1055/s-2007-990843BibTex
@article{Iaroshenko2007Facil-1078, year={2007}, doi={10.1055/s-2007-990843}, title={Facile synthesis of fluorinated purines and thiapurines}, number={21}, volume={2007}, issn={0039-7881}, journal={Synthesis: journal of synthetic organic chemistry}, pages={3309--3318}, author={Iaroshenko, Viktor O. and Volochnyuk, Dmitriy M. and Wang, Yan and Vovk, Mikhail V. and Boiko, Vyacheslav J. and Rusanov, Eduard B. and Groth, Ulrich and Tolmachev, Andrei A.} }
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