Facile synthesis of fluorinated purines and thiapurines

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2007
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Iaroshenko, Viktor O.
Volochnyuk, Dmitriy M.
Vovk, Mikhail V.
Boiko, Vyacheslav J.
Rusanov, Eduard B.
Tolmachev, Andrei A.
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The reaction of 2-(dialkylamino)-1,3-thiazol-4-amines and 1,2-dimethyl-IH-imidazol-5-amine with aryl isocyanates, alpha-chloroalkyl isocyanates, N-(alkoxycarbonyl)imidoyl chlorides and 2,4,6-tris(trifluoromethyl)-1,3,5-triazine leads to thiapurines and purines containing trifluoromethyl groups in the 2- and 6-positions of the pyrimidine ring.

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540 Chemie
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imidazole, thiazole, pyrimidine, isocyanate, annulation
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ISO 690IAROSHENKO, Viktor O., Dmitriy M. VOLOCHNYUK, Yan WANG, Mikhail V. VOVK, Vyacheslav J. BOIKO, Eduard B. RUSANOV, Ulrich GROTH, Andrei A. TOLMACHEV, 2007. Facile synthesis of fluorinated purines and thiapurines. In: Synthesis: journal of synthetic organic chemistry. 2007, 2007(21), pp. 3309-3318. ISSN 0039-7881. eISSN 1437-210X. Available under: doi: 10.1055/s-2007-990843
BibTex
@article{Iaroshenko2007Facil-1078,
  year={2007},
  doi={10.1055/s-2007-990843},
  title={Facile synthesis of fluorinated purines and thiapurines},
  number={21},
  volume={2007},
  issn={0039-7881},
  journal={Synthesis: journal of synthetic organic chemistry},
  pages={3309--3318},
  author={Iaroshenko, Viktor O. and Volochnyuk, Dmitriy M. and Wang, Yan and Vovk, Mikhail V. and Boiko, Vyacheslav J. and Rusanov, Eduard B. and Groth, Ulrich and Tolmachev, Andrei A.}
}
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