Geographic range expansion of tetrodotoxin in amphibians : First record in Atelopus hoogmoedi from the Guiana Shield

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dc.contributor.authorMebs, Dietrich
dc.contributor.authorLorentz, Max
dc.contributor.authorYotsu-Yamashita, Mari
dc.contributor.authorRößler, Daniela C.
dc.contributor.authorErnst, Raffael
dc.contributor.authorLötters, Stefan
dc.date.accessioned2021-07-19T08:20:05Z
dc.date.available2021-07-19T08:20:05Z
dc.date.issued2018eng
dc.description.abstractFor the first time, alcohol extracts of Atelopus hoogmoedi from the Guiana Shield in Suriname and Guyana were analyzed for the presence of tetrodotoxin (TTX) and of its analogues by high resolution hydrophilic interaction liquid chromatography/mass spectrometry. One specimen from Suriname was found to contain TTX and 4-epiTTX. Using a monoclonal antibody-based immunohistochemical staining technique, TTX was localized mainly in the granular glands and epithelium of the skin, but not in internal organs except liver showing weak TTX-positive reaction. In two specimens collected in Guyana, none of the toxins were detected.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1016/j.toxicon.2018.05.011eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/54345
dc.language.isoengeng
dc.rightsterms-of-use
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/
dc.subjectAtelopus hoogmoedi, Tetrodotoxin, Tissue distribution, Monoclonal antibody, Guiana Shieldeng
dc.subject.ddc570eng
dc.titleGeographic range expansion of tetrodotoxin in amphibians : First record in Atelopus hoogmoedi from the Guiana Shieldeng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Mebs2018Geogr-54345,
  year={2018},
  doi={10.1016/j.toxicon.2018.05.011},
  title={Geographic range expansion of tetrodotoxin in amphibians : First record in Atelopus hoogmoedi from the Guiana Shield},
  volume={150},
  issn={0041-0101},
  journal={Toxicon},
  pages={175--179},
  author={Mebs, Dietrich and Lorentz, Max and Yotsu-Yamashita, Mari and Rößler, Daniela C. and Ernst, Raffael and Lötters, Stefan}
}
kops.citation.iso690MEBS, Dietrich, Max LORENTZ, Mari YOTSU-YAMASHITA, Daniela C. RÖSSLER, Raffael ERNST, Stefan LÖTTERS, 2018. Geographic range expansion of tetrodotoxin in amphibians : First record in Atelopus hoogmoedi from the Guiana Shield. In: Toxicon. Elsevier. 2018, 150, pp. 175-179. ISSN 0041-0101. eISSN 1879-3150. Available under: doi: 10.1016/j.toxicon.2018.05.011deu
kops.citation.iso690MEBS, Dietrich, Max LORENTZ, Mari YOTSU-YAMASHITA, Daniela C. RÖSSLER, Raffael ERNST, Stefan LÖTTERS, 2018. Geographic range expansion of tetrodotoxin in amphibians : First record in Atelopus hoogmoedi from the Guiana Shield. In: Toxicon. Elsevier. 2018, 150, pp. 175-179. ISSN 0041-0101. eISSN 1879-3150. Available under: doi: 10.1016/j.toxicon.2018.05.011eng
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