Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase

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dc.contributor.authorSokolov, Valerij S.deu
dc.contributor.authorLenz, Alexander A.deu
dc.contributor.authorApell, Hans-Jürgen
dc.date.accessioned2011-03-24T17:41:16Zdeu
dc.date.available2011-03-24T17:41:16Zdeu
dc.date.issued2003deu
dc.description.abstractElectrogenic Na+ transport was investigated in membrane fragments containing Na,K-ATPase adsorbed to bilayer lipid membranes (BLM) triggered by fast ATP release from caged ATP. The influence of voltage on the transport after ATP release was determined as small increaments of capacitance and conductance by applying an alternating voltage to the membrane. An electrogenic Na+ transport through a cytoplasmic access channel of the Na,K-ATPase was detected that disappeared after enzyme phosphorylation, and thus produced a negative capacitance and conductance increaments at Na+ concentrations below 5 mM3. This effect was studied now in more detail by measuring the frequency dependence of the capacitance and conductance increaments at different Na+ concentrations.eng
dc.description.versionpublished
dc.format.mimetypeapplication/pdfdeu
dc.identifier.citationFirst publ. in: Annals of the New York Academy of Science 986 (2003), pp. 229-231deu
dc.identifier.doi10.1111/j.1749-6632.2003.tb07166.x
dc.identifier.ppn273277898deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/8187
dc.language.isoengdeu
dc.legacy.dateIssued2007deu
dc.rightsAttribution-NonCommercial-NoDerivs 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/
dc.subjectNa,K-ATPasedeu
dc.subjectelectrogenicitydeu
dc.subjectcapacitancedeu
dc.subjectNa+ movementsdeu
dc.subjection bindingdeu
dc.subject.ddc570deu
dc.titleNegative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPaseeng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
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@article{Sokolov2003Negat-8187,
  year={2003},
  doi={10.1111/j.1749-6632.2003.tb07166.x},
  title={Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase},
  number={1},
  volume={986},
  issn={0077-8923},
  journal={Annals of the New York Academy of Science},
  pages={229--231},
  author={Sokolov, Valerij S. and Lenz, Alexander A. and Apell, Hans-Jürgen}
}
kops.citation.iso690SOKOLOV, Valerij S., Alexander A. LENZ, Hans-Jürgen APELL, 2003. Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase. In: Annals of the New York Academy of Science. 2003, 986(1), pp. 229-231. ISSN 0077-8923. eISSN 1749-6632. Available under: doi: 10.1111/j.1749-6632.2003.tb07166.xdeu
kops.citation.iso690SOKOLOV, Valerij S., Alexander A. LENZ, Hans-Jürgen APELL, 2003. Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase. In: Annals of the New York Academy of Science. 2003, 986(1), pp. 229-231. ISSN 0077-8923. eISSN 1749-6632. Available under: doi: 10.1111/j.1749-6632.2003.tb07166.xeng
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