Publikation:

Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase

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Datum

2003

Autor:innen

Sokolov, Valerij S.
Lenz, Alexander A.

Herausgeber:innen

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URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-39388
DOI (zitierfähiger Link)
https://doi.org/10.1111/j.1749-6632.2003.tb07166.x
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Attribution-NonCommercial-NoDerivs 2.0 Generic

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Open Access-Veröffentlichung
Open Access Green

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Biologie: Publikationen
Core Facility der Universität Konstanz

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Titel in einer weiteren Sprache

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Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Annals of the New York Academy of Science. 2003, 986(1), pp. 229-231. ISSN 0077-8923. eISSN 1749-6632. Available under: doi: 10.1111/j.1749-6632.2003.tb07166.x

Zusammenfassung

Electrogenic Na+ transport was investigated in membrane fragments containing Na,K-ATPase adsorbed to bilayer lipid membranes (BLM) triggered by fast ATP release from caged ATP. The influence of voltage on the transport after ATP release was determined as small increaments of capacitance and conductance by applying an alternating voltage to the membrane. An electrogenic Na+ transport through a cytoplasmic access channel of the Na,K-ATPase was detected that disappeared after enzyme phosphorylation, and thus produced a negative capacitance and conductance increaments at Na+ concentrations below 5 mM3. This effect was studied now in more detail by measuring the frequency dependence of the capacitance and conductance increaments at different Na+ concentrations.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Na,K-ATPase, electrogenicity, capacitance, Na+ movements, ion binding

Konferenz

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Zeitschriftenheft

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Zitieren

ISO 690SOKOLOV, Valerij S., Alexander A. LENZ, Hans-Jürgen APELL, 2003. Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase. In: Annals of the New York Academy of Science. 2003, 986(1), pp. 229-231. ISSN 0077-8923. eISSN 1749-6632. Available under: doi: 10.1111/j.1749-6632.2003.tb07166.x
BibTex
@article{Sokolov2003Negat-8187,
  year={2003},
  doi={10.1111/j.1749-6632.2003.tb07166.x},
  title={Negative Changes of the Membrane Capacitance due to Electrogenic Na Transport by the Na, K-ATPase},
  number={1},
  volume={986},
  issn={0077-8923},
  journal={Annals of the New York Academy of Science},
  pages={229--231},
  author={Sokolov, Valerij S. and Lenz, Alexander A. and Apell, Hans-Jürgen}
}
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