Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening

Kurzanzeige
dc.contributor.authorSvetlik, Jandeu
dc.contributor.authorVeizerová, Luciadeu
dc.contributor.authorMayer, Thomas U.
dc.contributor.authorCatarinella, Mario
dc.date.accessioned2011-06-21T07:34:25Zdeu
dc.date.available2011-06-21T07:34:25Zdeu
dc.date.issued2010-07-15
dc.description.abstractA synthesis of novel pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged pyrazolo-, tetrazolo-, benzimidazo-, and thiazolopyrimidines via Hantzsch- and Biginelli-like condensations has been developed. The ability of these compounds to inhibit Eg5 activity has been examined. The results indicate that synthetic manipulations in the monastrol thiourea moiety are inefficient.eng
dc.description.versionpublished
dc.identifier.citationFirst publ. in: Bioorganic & Medicinal Chemistry Letters 20 (2010), 14, pp. 4073-4076deu
dc.identifier.doi10.1016/j.bmcl.2010.05.085deu
dc.identifier.pmid20542426
dc.identifier.ppn346231884deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/12548
dc.language.isoengdeu
dc.legacy.dateIssued2011-06-21deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectBiginelli reactiondeu
dc.subjectHantzsch reactiondeu
dc.subjectOxygen-bridged nitrogen heterocyclesdeu
dc.subjectMonastrol analogsdeu
dc.subject.ddc570deu
dc.titleMonastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screeningeng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
@article{Svetlik2010-07-15Monas-12548,
  year={2010},
  doi={10.1016/j.bmcl.2010.05.085},
  title={Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening},
  number={14},
  volume={20},
  issn={0960-894X},
  journal={Bioorganic & Medicinal Chemistry Letters},
  pages={4073--4076},
  author={Svetlik, Jan and Veizerová, Lucia and Mayer, Thomas U. and Catarinella, Mario}
}
kops.citation.iso690SVETLIK, Jan, Lucia VEIZEROVÁ, Thomas U. MAYER, Mario CATARINELLA, 2010. Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening. In: Bioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085deu
kops.citation.iso690SVETLIK, Jan, Lucia VEIZEROVÁ, Thomas U. MAYER, Mario CATARINELLA, 2010. Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening. In: Bioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085eng
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kops.sourcefieldBioorganic & Medicinal Chemistry Letters. 2010, <b>20</b>(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085deu
kops.sourcefield.plainBioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085deu
kops.sourcefield.plainBioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085eng
kops.submitter.emailmichael.ketzer@uni-konstanz.dedeu
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source.periodicalTitleBioorganic & Medicinal Chemistry Letters

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