Publikation:

Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening

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Datum

2010

Autor:innen

Svetlik, Jan
Veizerová, Lucia

Herausgeber:innen

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URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-125486
DOI (zitierfähiger Link)
https://doi.org/10.1016/j.bmcl.2010.05.085
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Urheberrechtlich geschützt

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Open Access-Veröffentlichung
Open Access Green

Sammlungen

Biologie: Publikationen
Core Facility der Universität Konstanz

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Titel in einer weiteren Sprache

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Zeitschriftenartikel
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Published

Erschienen in

Bioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085

Zusammenfassung

A synthesis of novel pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged pyrazolo-, tetrazolo-, benzimidazo-, and thiazolopyrimidines via Hantzsch- and Biginelli-like condensations has been developed. The ability of these compounds to inhibit Eg5 activity has been examined. The results indicate that synthetic manipulations in the monastrol thiourea moiety are inefficient.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Biginelli reaction, Hantzsch reaction, Oxygen-bridged nitrogen heterocycles, Monastrol analogs

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ISO 690SVETLIK, Jan, Lucia VEIZEROVÁ, Thomas U. MAYER, Mario CATARINELLA, 2010. Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening. In: Bioorganic & Medicinal Chemistry Letters. 2010, 20(14), pp. 4073-4076. ISSN 0960-894X. eISSN 1464-3405. Available under: doi: 10.1016/j.bmcl.2010.05.085
BibTex
@article{Svetlik2010-07-15Monas-12548,
  year={2010},
  doi={10.1016/j.bmcl.2010.05.085},
  title={Monastrol analogs : a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening},
  number={14},
  volume={20},
  issn={0960-894X},
  journal={Bioorganic & Medicinal Chemistry Letters},
  pages={4073--4076},
  author={Svetlik, Jan and Veizerová, Lucia and Mayer, Thomas U. and Catarinella, Mario}
}
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