Detection and Evaluation of Proliferating Cell Nuclear Antigen (PCNA) in Rat Tissue by an Improved Immunohistochemical Procedure

Kurzanzeige
dc.contributor.authorFoley, Julie F.deu
dc.contributor.authorDietrich, Daniel R.
dc.contributor.authorSwenberg, James A.deu
dc.contributor.authorMaronpot, Robert R.deu
dc.date.accessioned2011-03-24T17:46:01Zdeu
dc.date.available2011-03-24T17:46:01Zdeu
dc.date.issued1991deu
dc.description.abstractProliferating cell nuclear antigen (PCNA), an endogenous cell replication marker, was detected by an improved immunohistochemical procedure (super sensitive biotin-streptavidin), in formalin fixed, paraffin embedded tissue. Small intestine, liver, kidney, testis, and esophagus from rats were stained for the detection and evaluation of PCNA as asuitable marker for cell proliferation. Different patterns of staining that are believed to correlate with the individual phases of the cell cycle (G1, S, G2, M, G0) were recognized. PCNA offers an alternative to established cell labeling techniques for investigating cell proliferation.eng
dc.description.versionpublished
dc.format.mimetypeapplication/pdfdeu
dc.identifier.citationFirst publ. in: Journal of Histotechnology 14 (1991), 4, pp. 237-241deu
dc.identifier.doi10.1179/his.1991.14.4.237
dc.identifier.ppn278068820deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/8729
dc.language.isoengdeu
dc.legacy.dateIssued2008deu
dc.rightsAttribution-NonCommercial-NoDerivs 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/
dc.subjectformalin fixationdeu
dc.subjectparaffin processingdeu
dc.subjectproliferating cell nuclear antigendeu
dc.subjectsuper sensitive biotin-streptavidindeu
dc.subject.ddc570deu
dc.titleDetection and Evaluation of Proliferating Cell Nuclear Antigen (PCNA) in Rat Tissue by an Improved Immunohistochemical Procedureeng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
@article{Foley1991Detec-8729,
  year={1991},
  doi={10.1179/his.1991.14.4.237},
  title={Detection and Evaluation of Proliferating Cell Nuclear Antigen (PCNA) in Rat Tissue by an Improved Immunohistochemical Procedure},
  number={4},
  volume={14},
  issn={0147-8885},
  journal={Journal of Histotechnology},
  pages={237--241},
  author={Foley, Julie F. and Dietrich, Daniel R. and Swenberg, James A. and Maronpot, Robert R.}
}
kops.citation.iso690FOLEY, Julie F., Daniel R. DIETRICH, James A. SWENBERG, Robert R. MARONPOT, 1991. Detection and Evaluation of Proliferating Cell Nuclear Antigen (PCNA) in Rat Tissue by an Improved Immunohistochemical Procedure. In: Journal of Histotechnology. 1991, 14(4), pp. 237-241. ISSN 0147-8885. eISSN 2046-0236. Available under: doi: 10.1179/his.1991.14.4.237deu
kops.citation.iso690FOLEY, Julie F., Daniel R. DIETRICH, James A. SWENBERG, Robert R. MARONPOT, 1991. Detection and Evaluation of Proliferating Cell Nuclear Antigen (PCNA) in Rat Tissue by an Improved Immunohistochemical Procedure. In: Journal of Histotechnology. 1991, 14(4), pp. 237-241. ISSN 0147-8885. eISSN 2046-0236. Available under: doi: 10.1179/his.1991.14.4.237eng
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