Evolving a thermostable DNA polymerase that amplifies from highly damaged templates

Kurzanzeige
dc.contributor.authorGlöckner, Christiandeu
dc.contributor.authorSauter, Katharina B.deu
dc.contributor.authorMarx, Andreas
dc.date.accessioned2011-11-16T09:10:07Zdeu
dc.date.available2011-11-16T09:10:07Zdeu
dc.date.issued2007
dc.description.abstractThe foreign lesion: DNAs with damage generated, for example, by UV light are not good targets for standard replicative DNA polymerases. A DNA polymerase has been derived by directed evolution that faithfully amplifies light-damaged DNA. Interestingly, a single mutation is sufficient for this propertyeng
dc.description.versionpublished
dc.identifier.citationPubl. in: Angewandte Chemie / International Edition ; 46 (2007), 17. - S. 3115-3117deu
dc.identifier.doi10.1002/anie.200603987deu
dc.identifier.pmid17366498
dc.identifier.ppn469802162
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/16698
dc.language.isoengdeu
dc.legacy.dateIssued2011-11-16deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectdirected evolutiondeu
dc.subjectDNA damagedeu
dc.subjectDNA polymerasedeu
dc.subjectpolymerase chain reactiondeu
dc.subject.ddc540deu
dc.titleEvolving a thermostable DNA polymerase that amplifies from highly damaged templateseng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
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  year={2007},
  doi={10.1002/anie.200603987},
  title={Evolving a thermostable DNA polymerase that amplifies from highly damaged templates},
  number={17},
  volume={46},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={3115--3117},
  author={Glöckner, Christian and Sauter, Katharina B. and Marx, Andreas}
}
kops.citation.iso690GLÖCKNER, Christian, Katharina B. SAUTER, Andreas MARX, 2007. Evolving a thermostable DNA polymerase that amplifies from highly damaged templates. In: Angewandte Chemie International Edition. 2007, 46(17), pp. 3115-3117. ISSN 1433-7851. Available under: doi: 10.1002/anie.200603987deu
kops.citation.iso690GLÖCKNER, Christian, Katharina B. SAUTER, Andreas MARX, 2007. Evolving a thermostable DNA polymerase that amplifies from highly damaged templates. In: Angewandte Chemie International Edition. 2007, 46(17), pp. 3115-3117. ISSN 1433-7851. Available under: doi: 10.1002/anie.200603987eng
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kops.sourcefieldAngewandte Chemie International Edition. 2007, <b>46</b>(17), pp. 3115-3117. ISSN 1433-7851. Available under: doi: 10.1002/anie.200603987deu
kops.sourcefield.plainAngewandte Chemie International Edition. 2007, 46(17), pp. 3115-3117. ISSN 1433-7851. Available under: doi: 10.1002/anie.200603987deu
kops.sourcefield.plainAngewandte Chemie International Edition. 2007, 46(17), pp. 3115-3117. ISSN 1433-7851. Available under: doi: 10.1002/anie.200603987eng
kops.submitter.emailkaren-ann.lindner@uni-konstanz.dedeu
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