CCR7 : Roles in cancer cell dissemination, migration and metastasis formation

Kurzanzeige
dc.contributor.authorLegler, Daniel F.
dc.contributor.authorUetz-von Allmen, Edith
dc.contributor.authorHauser, Mark A.
dc.date.accessioned2014-11-27T10:10:19Z
dc.date.available2014-11-27T10:10:19Z
dc.date.issued2014eng
dc.description.abstractThe CC-chemokine receptor 7 (CCR7) coordinates the migration of cancer cells as well as immune cells towards lymphatic organs where its two ligands CCL19 and CCL21 are constitutively expressed. Here we provide a topological model of CCR7, which belongs to the class A of G-protein coupled, seven-transmembrane spanning receptors, and describe how CCR7 expression is regulated. We focus on its role in cancer cell migration and metastasis formation and discuss how cancer cells can utilize CCR7 or its ligands to escape from immune surveillance.eng
dc.description.versionpublished
dc.identifier.doi10.1016/j.biocel.2014.07.002eng
dc.identifier.ppn483498955
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/29330
dc.language.isoengeng
dc.rightsterms-of-use
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/
dc.subjectChemokine receptor, Cancer, Metastasis formation, Cell migration, Lymph node homingeng
dc.subject.ddc570eng
dc.titleCCR7 : Roles in cancer cell dissemination, migration and metastasis formationeng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Legler2014Roles-29330,
  year={2014},
  doi={10.1016/j.biocel.2014.07.002},
  title={CCR7 : Roles in cancer cell dissemination, migration and metastasis formation},
  volume={54},
  issn={1357-2725},
  journal={The International Journal of Biochemistry & Cell Biology},
  pages={78--82},
  author={Legler, Daniel F. and Uetz-von Allmen, Edith and Hauser, Mark A.}
}
kops.citation.iso690LEGLER, Daniel F., Edith UETZ-VON ALLMEN, Mark A. HAUSER, 2014. CCR7 : Roles in cancer cell dissemination, migration and metastasis formation. In: The International Journal of Biochemistry & Cell Biology. 2014, 54, pp. 78-82. ISSN 1357-2725. eISSN 1878-5875. Available under: doi: 10.1016/j.biocel.2014.07.002deu
kops.citation.iso690LEGLER, Daniel F., Edith UETZ-VON ALLMEN, Mark A. HAUSER, 2014. CCR7 : Roles in cancer cell dissemination, migration and metastasis formation. In: The International Journal of Biochemistry & Cell Biology. 2014, 54, pp. 78-82. ISSN 1357-2725. eISSN 1878-5875. Available under: doi: 10.1016/j.biocel.2014.07.002eng
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kops.sourcefieldThe International Journal of Biochemistry & Cell Biology. 2014, <b>54</b>, pp. 78-82. ISSN 1357-2725. eISSN 1878-5875. Available under: doi: 10.1016/j.biocel.2014.07.002deu
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kops.sourcefield.plainThe International Journal of Biochemistry & Cell Biology. 2014, 54, pp. 78-82. ISSN 1357-2725. eISSN 1878-5875. Available under: doi: 10.1016/j.biocel.2014.07.002eng
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temp.internal.duplicates<p>Keine Dubletten gefunden. Letzte Überprüfung: 11.11.2014 12:18:10</p>deu

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