Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants

Kurzanzeige
dc.contributor.authorReddy, B. Gopal
dc.contributor.authorSilk, Jonathan D.
dc.contributor.authorSalio, Mariolina
dc.contributor.authorBalamurugan, Rengarajan
dc.contributor.authorShepherd, Dawn
dc.contributor.authorRitter, Gerd
dc.contributor.authorCerundolo, Vincenzo
dc.contributor.authorSchmidt, Richard R.
dc.date.accessioned2022-07-26T12:36:55Z
dc.date.available2022-07-26T12:36:55Z
dc.date.issued2009-02eng
dc.description.abstractBased on the crystal structures of human α-GalCer–CD1d and iNKT–α-GalCer–CD1d complexes, nonglycosidic analogues of α-GalCer were synthesized. They activate iNKT cells resulting in dendritic cell maturation and the priming of antigen-specific T and B cells. Therefore, they are attractive adjuvants in vaccination strategies for cancer and infectious diseases.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1002/cmdc.200800354eng
dc.identifier.pmid19160440eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/58157
dc.language.isoengeng
dc.subject.ddc540eng
dc.titleNonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvantseng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Reddy2009-02Nongl-58157,
  year={2009},
  doi={10.1002/cmdc.200800354},
  title={Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants},
  number={2},
  volume={4},
  issn={1860-7179},
  journal={ChemMedChem},
  pages={171--175},
  author={Reddy, B. Gopal and Silk, Jonathan D. and Salio, Mariolina and Balamurugan, Rengarajan and Shepherd, Dawn and Ritter, Gerd and Cerundolo, Vincenzo and Schmidt, Richard R.}
}
kops.citation.iso690REDDY, B. Gopal, Jonathan D. SILK, Mariolina SALIO, Rengarajan BALAMURUGAN, Dawn SHEPHERD, Gerd RITTER, Vincenzo CERUNDOLO, Richard R. SCHMIDT, 2009. Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants. In: ChemMedChem. Wiley. 2009, 4(2), pp. 171-175. ISSN 1860-7179. eISSN 1860-7187. Available under: doi: 10.1002/cmdc.200800354deu
kops.citation.iso690REDDY, B. Gopal, Jonathan D. SILK, Mariolina SALIO, Rengarajan BALAMURUGAN, Dawn SHEPHERD, Gerd RITTER, Vincenzo CERUNDOLO, Richard R. SCHMIDT, 2009. Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants. In: ChemMedChem. Wiley. 2009, 4(2), pp. 171-175. ISSN 1860-7179. eISSN 1860-7187. Available under: doi: 10.1002/cmdc.200800354eng
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kops.sourcefieldChemMedChem. Wiley. 2009, <b>4</b>(2), pp. 171-175. ISSN 1860-7179. eISSN 1860-7187. Available under: doi: 10.1002/cmdc.200800354deu
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