Expression and subcellular localization of mouse 20S proteasome activator complex PA28

Kurzanzeige
dc.contributor.authorSoza, Andreadeu
dc.contributor.authorKnuehl, Christinedeu
dc.contributor.authorGroettrup, Marcus
dc.contributor.authorHenklein, Peterdeu
dc.contributor.authorTanaka, Keijideu
dc.contributor.authorKloetzel, Peter M.deu
dc.date.accessioned2013-04-02T18:48:06Zdeu
dc.date.available2013-04-02T18:48:06Zdeu
dc.date.issued1997
dc.description.abstractWe have cloned the mouse PA28 proteasome activator cDNAs. Northern blot demonstrates high PA28 mRNA levels in liver, kidney and lung. mRNA levels are low in thymus, spleen and brain. In contrast, PA28 protein levels vary little between these tissues. Immunocytological analysis and cell fractionation experiments demonstrate that both subunits are almost equally distributed between the cytoplasm and the nucleus. Interestingly, PA28alpha spares nucleoli, while PA28beta is strongly enhanced in the nucleolus. This indicates for the first time that the PA28alpha and PA28beta subunits may serve nuclear functions which may be different from and independent of each other.eng
dc.description.versionpublished
dc.identifier.citationFEBS Letters ; 413 (1997), 1. - S. 27-34deu
dc.identifier.doi10.1016/S0014-5793(97)00864-8deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/22244
dc.language.isoengdeu
dc.legacy.dateIssued2013-04-02deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectProteasomedeu
dc.subjectActivatordeu
dc.subjectKi-autoantigendeu
dc.subject.ddc570deu
dc.titleExpression and subcellular localization of mouse 20S proteasome activator complex PA28eng
dc.typeJOURNAL_ARTICLEdeu
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@article{Soza1997Expre-22244,
  year={1997},
  doi={10.1016/S0014-5793(97)00864-8},
  title={Expression and subcellular localization of mouse 20S proteasome activator complex PA28},
  number={1},
  volume={413},
  issn={0014-5793},
  journal={FEBS Letters},
  pages={27--34},
  author={Soza, Andrea and Knuehl, Christine and Gröttrup, Marcus and Henklein, Peter and Tanaka, Keiji and Kloetzel, Peter M.}
}
kops.citation.iso690SOZA, Andrea, Christine KNUEHL, Marcus GRÖTTRUP, Peter HENKLEIN, Keiji TANAKA, Peter M. KLOETZEL, 1997. Expression and subcellular localization of mouse 20S proteasome activator complex PA28. In: FEBS Letters. 1997, 413(1), pp. 27-34. ISSN 0014-5793. eISSN 1873-3468. Available under: doi: 10.1016/S0014-5793(97)00864-8deu
kops.citation.iso690SOZA, Andrea, Christine KNUEHL, Marcus GRÖTTRUP, Peter HENKLEIN, Keiji TANAKA, Peter M. KLOETZEL, 1997. Expression and subcellular localization of mouse 20S proteasome activator complex PA28. In: FEBS Letters. 1997, 413(1), pp. 27-34. ISSN 0014-5793. eISSN 1873-3468. Available under: doi: 10.1016/S0014-5793(97)00864-8eng
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kops.sourcefield.plainFEBS Letters. 1997, 413(1), pp. 27-34. ISSN 0014-5793. eISSN 1873-3468. Available under: doi: 10.1016/S0014-5793(97)00864-8eng
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