Chemical genetics : tailoring tools for cell biology

Kurzanzeige
dc.contributor.authorMayer, Thomas U.
dc.date.accessioned2012-01-04T13:21:41Zdeu
dc.date.available2012-01-04T13:21:41Zdeu
dc.date.issued2003
dc.description.abstractChemical genetics is a research approach that uses small molecules as probes to study protein functions in cells or whole organisms. Here, I review the parallels between classical genetic and chemical-genetic approaches and discuss the merits of small molecules to dissect dynamic cellular processes. I then consider the pros and cons of different screening approaches and specify strategies aimed at identifying and validating cellular target proteins. Finally, I highlight the impact of chemical genetics on our current understanding of cell biology and its potential for the future.eng
dc.description.versionpublished
dc.identifier.citationTrends Cell Biology ; 13 (2003), 5. - S. 270-277deu
dc.identifier.doi10.1016/S0962-8924(03)00077-1deu
dc.identifier.ppn377829307deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/14052
dc.language.isoengdeu
dc.legacy.dateIssued2012-01-04deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectsmall moleculedeu
dc.subjectEg5deu
dc.subjectKinesindeu
dc.subjectChemical Biologydeu
dc.subject.ddc570deu
dc.titleChemical genetics : tailoring tools for cell biologyeng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
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  year={2003},
  doi={10.1016/S0962-8924(03)00077-1},
  title={Chemical genetics : tailoring tools for cell biology},
  number={5},
  volume={13},
  issn={0962-8924},
  journal={Trends in Cell Biology},
  pages={270--277},
  author={Mayer, Thomas U.}
}
kops.citation.iso690MAYER, Thomas U., 2003. Chemical genetics : tailoring tools for cell biology. In: Trends in Cell Biology. 2003, 13(5), pp. 270-277. ISSN 0962-8924. Available under: doi: 10.1016/S0962-8924(03)00077-1deu
kops.citation.iso690MAYER, Thomas U., 2003. Chemical genetics : tailoring tools for cell biology. In: Trends in Cell Biology. 2003, 13(5), pp. 270-277. ISSN 0962-8924. Available under: doi: 10.1016/S0962-8924(03)00077-1eng
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kops.sourcefieldTrends in Cell Biology. 2003, <b>13</b>(5), pp. 270-277. ISSN 0962-8924. Available under: doi: 10.1016/S0962-8924(03)00077-1deu
kops.sourcefield.plainTrends in Cell Biology. 2003, 13(5), pp. 270-277. ISSN 0962-8924. Available under: doi: 10.1016/S0962-8924(03)00077-1deu
kops.sourcefield.plainTrends in Cell Biology. 2003, 13(5), pp. 270-277. ISSN 0962-8924. Available under: doi: 10.1016/S0962-8924(03)00077-1eng
kops.submitter.emailmarcus.beck@uni-konstanz.dedeu
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