Graph Kernels for Molecular Similarity

dc.contributor.authorRupp, Matthias
dc.contributor.authorSchneider, Gisbert
dc.date.accessioned2020-12-22T13:28:49Z
dc.date.available2020-12-22T13:28:49Z
dc.date.issued2010-04-12eng
dc.description.abstractMolecular similarity measures are important for many cheminformatics applications like ligand‐based virtual screening and quantitative structure‐property relationships. Graph kernels are formal similarity measures defined directly on graphs, such as the (annotated) molecular structure graph. Graph kernels are positive semi‐definite functions, i.e., they correspond to inner products. This property makes them suitable for use with kernel‐based machine learning algorithms such as support vector machines and Gaussian processes. We review the major types of kernels between graphs (based on random walks, subgraphs, and optimal assignments, respectively), and discuss their advantages, limitations, and successful applications in cheminformatics.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1002/minf.200900080eng
dc.identifier.pmid27463053eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/52230
dc.language.isoengeng
dc.rightsterms-of-use
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dc.subjectGraph kernels, Molecular similarity, Machine learning, Structure grapheng
dc.subject.ddc004eng
dc.titleGraph Kernels for Molecular Similarityeng
dc.typeJOURNAL_ARTICLEeng
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@article{Rupp2010-04-12Graph-52230,
  year={2010},
  doi={10.1002/minf.200900080},
  title={Graph Kernels for Molecular Similarity},
  number={4},
  volume={29},
  issn={1868-1743},
  journal={Molecular Informatics},
  pages={266--273},
  author={Rupp, Matthias and Schneider, Gisbert}
}
kops.citation.iso690RUPP, Matthias, Gisbert SCHNEIDER, 2010. Graph Kernels for Molecular Similarity. In: Molecular Informatics. Wiley. 2010, 29(4), pp. 266-273. ISSN 1868-1743. eISSN 1868-1751. Available under: doi: 10.1002/minf.200900080deu
kops.citation.iso690RUPP, Matthias, Gisbert SCHNEIDER, 2010. Graph Kernels for Molecular Similarity. In: Molecular Informatics. Wiley. 2010, 29(4), pp. 266-273. ISSN 1868-1743. eISSN 1868-1751. Available under: doi: 10.1002/minf.200900080eng
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    <dcterms:abstract xml:lang="eng">Molecular similarity measures are important for many cheminformatics applications like ligand‐based virtual screening and quantitative structure‐property relationships. Graph kernels are formal similarity measures defined directly on graphs, such as the (annotated) molecular structure graph. Graph kernels are positive semi‐definite functions, i.e., they correspond to inner products. This property makes them suitable for use with kernel‐based machine learning algorithms such as support vector machines and Gaussian processes. We review the major types of kernels between graphs (based on random walks, subgraphs, and optimal assignments, respectively), and discuss their advantages, limitations, and successful applications in cheminformatics.</dcterms:abstract>
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kops.sourcefieldMolecular Informatics. Wiley. 2010, <b>29</b>(4), pp. 266-273. ISSN 1868-1743. eISSN 1868-1751. Available under: doi: 10.1002/minf.200900080deu
kops.sourcefield.plainMolecular Informatics. Wiley. 2010, 29(4), pp. 266-273. ISSN 1868-1743. eISSN 1868-1751. Available under: doi: 10.1002/minf.200900080deu
kops.sourcefield.plainMolecular Informatics. Wiley. 2010, 29(4), pp. 266-273. ISSN 1868-1743. eISSN 1868-1751. Available under: doi: 10.1002/minf.200900080eng
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source.periodicalTitleMolecular Informaticseng
source.publisherWileyeng

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