CEACAMs : their role in physiology and pathophysiology
| dc.contributor.author | Kuespert, Katharina | deu |
| dc.contributor.author | Pils, Stefan | |
| dc.contributor.author | Hauck, Christof R. | |
| dc.date.accessioned | 2011-03-24T17:41:39Z | deu |
| dc.date.available | 2011-03-24T17:41:39Z | deu |
| dc.date.issued | 2006 | deu |
| dc.description.abstract | Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAMs have also been identified as receptors for host-specific viruses and bacteria in mice and humans, respectively, making these proteins an interesting example of pathogen host co-evolution. Forward and reverse genetics in the mouse now provide powerful novel models to elucidate the action of CEACAM family members in vivo. | eng |
| dc.description.version | published | |
| dc.format.mimetype | application/pdf | deu |
| dc.identifier.citation | First publ. in: Current Opinion in Cell Biology 18 (2006), 5, pp. 565 571 | deu |
| dc.identifier.doi | 10.1016/j.ceb.2006.08.008 | |
| dc.identifier.pmid | 16919437 | |
| dc.identifier.ppn | 274401878 | deu |
| dc.identifier.uri | http://kops.uni-konstanz.de/handle/123456789/8236 | |
| dc.language.iso | eng | deu |
| dc.legacy.dateIssued | 2007 | deu |
| dc.rights | Attribution-NonCommercial-NoDerivs 2.0 Generic | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.0/ | |
| dc.subject.ddc | 570 | deu |
| dc.title | CEACAMs : their role in physiology and pathophysiology | eng |
| dc.type | JOURNAL_ARTICLE | deu |
| dspace.entity.type | Publication | |
| kops.citation.bibtex | @article{Kuespert2006CEACA-8236,
year={2006},
doi={10.1016/j.ceb.2006.08.008},
title={CEACAMs : their role in physiology and pathophysiology},
number={5},
volume={18},
issn={0955-0674},
journal={Current Opinion in Cell Biology},
pages={565--571},
author={Kuespert, Katharina and Pils, Stefan and Hauck, Christof R.}
} | |
| kops.citation.iso690 | KUESPERT, Katharina, Stefan PILS, Christof R. HAUCK, 2006. CEACAMs : their role in physiology and pathophysiology. In: Current Opinion in Cell Biology. 2006, 18(5), pp. 565-571. ISSN 0955-0674. Available under: doi: 10.1016/j.ceb.2006.08.008 | deu |
| kops.citation.iso690 | KUESPERT, Katharina, Stefan PILS, Christof R. HAUCK, 2006. CEACAMs : their role in physiology and pathophysiology. In: Current Opinion in Cell Biology. 2006, 18(5), pp. 565-571. ISSN 0955-0674. Available under: doi: 10.1016/j.ceb.2006.08.008 | eng |
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<dcterms:abstract xml:lang="eng">Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAMs have also been identified as receptors for host-specific viruses and bacteria in mice and humans, respectively, making these proteins an interesting example of pathogen host co-evolution. Forward and reverse genetics in the mouse now provide powerful novel models to elucidate the action of CEACAM family members in vivo.</dcterms:abstract>
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