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CEACAMs : their role in physiology and pathophysiology

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2006

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Current Opinion in Cell Biology. 2006, 18(5), pp. 565-571. ISSN 0955-0674. Available under: doi: 10.1016/j.ceb.2006.08.008

Zusammenfassung

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAMs have also been identified as receptors for host-specific viruses and bacteria in mice and humans, respectively, making these proteins an interesting example of pathogen host co-evolution. Forward and reverse genetics in the mouse now provide powerful novel models to elucidate the action of CEACAM family members in vivo.

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570 Biowissenschaften, Biologie

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ISO 690KUESPERT, Katharina, Stefan PILS, Christof R. HAUCK, 2006. CEACAMs : their role in physiology and pathophysiology. In: Current Opinion in Cell Biology. 2006, 18(5), pp. 565-571. ISSN 0955-0674. Available under: doi: 10.1016/j.ceb.2006.08.008
BibTex
@article{Kuespert2006CEACA-8236,
  year={2006},
  doi={10.1016/j.ceb.2006.08.008},
  title={CEACAMs : their role in physiology and pathophysiology},
  number={5},
  volume={18},
  issn={0955-0674},
  journal={Current Opinion in Cell Biology},
  pages={565--571},
  author={Kuespert, Katharina and Pils, Stefan and Hauck, Christof R.}
}
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