Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces

Kurzanzeige
dc.contributor.authorBornemann, Benjamindeu
dc.contributor.authorLiu, Shoupeng
dc.contributor.authorErbe, Artur
dc.contributor.authorScheer, Elke
dc.contributor.authorMarx, Andreas
dc.date.accessioned2011-03-24T17:55:42Zdeu
dc.date.available2011-03-24T17:55:42Zdeu
dc.date.issued2008deu
dc.description.abstractThiols have a strong tendency to be chemisorbed to gold surfaces forming self-assembled monolayers. The feature of strong S-Au bond formation has been exploited in numerous applications including the immobilisation of DNA on gold surfaces for the generation of DNA microarrays or gold electrodes for measuring charge migration mediated by double stranded DNA. To be immobilised on gold, DNA has to be modified with thiol functionalities. Usually, for this purpose oligonucleotides are equipped with thioalkyl moieties at the 5 - or 3 -terminus. These modifications have been employed in studies dedicated to directly measure electrical transport through DNA molecules.eng
dc.description.versionpublished
dc.format.mimetypeapplication/pdfdeu
dc.identifier.citationFirst publ. in: ChemPhysChem 9 (2008), 9, pp. 1241-1244deu
dc.identifier.doi10.1002/cphc.200800081
dc.identifier.ppn303051078deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/9344
dc.language.isoengdeu
dc.legacy.dateIssued2009deu
dc.rightsAttribution-NonCommercial-NoDerivs 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/
dc.subjectDNAdeu
dc.subjectfluorescencedeu
dc.subjectimmobilisationdeu
dc.subjectnucleosidedeu
dc.subjectthiol gold interactiondeu
dc.subject.ddc530deu
dc.titleThiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaceseng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
@article{Bornemann2008Thiol-9344,
  year={2008},
  doi={10.1002/cphc.200800081},
  title={Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces},
  number={9},
  volume={9},
  journal={ChemPhysChem},
  pages={1241--1244},
  author={Bornemann, Benjamin and Liu, Shoupeng and Erbe, Artur and Scheer, Elke and Marx, Andreas}
}
kops.citation.iso690BORNEMANN, Benjamin, Shoupeng LIU, Artur ERBE, Elke SCHEER, Andreas MARX, 2008. Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces. In: ChemPhysChem. 2008, 9(9), pp. 1241-1244. Available under: doi: 10.1002/cphc.200800081deu
kops.citation.iso690BORNEMANN, Benjamin, Shoupeng LIU, Artur ERBE, Elke SCHEER, Andreas MARX, 2008. Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces. In: ChemPhysChem. 2008, 9(9), pp. 1241-1244. Available under: doi: 10.1002/cphc.200800081eng
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