Publikation:

Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces

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Thiolated_Nucleotides_for_Immobilisation_of_DNA_Oligomers_on_Gold_Surfaces.pdf
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Datum

2008

Autor:innen

Bornemann, Benjamin

Herausgeber:innen

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ISBN

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URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-65323
DOI (zitierfähiger Link)
https://doi.org/10.1002/cphc.200800081
ArXiv-ID

Internationale Patentnummer

Link zur Lizenz
Attribution-NonCommercial-NoDerivs 2.0 Generic

Angaben zur Forschungsförderung

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Open Access-Veröffentlichung
Open Access Green

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Physik: Publikationen
Zukunftskolleg: Publikationen
Core Facility der Universität Konstanz

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Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

ChemPhysChem. 2008, 9(9), pp. 1241-1244. Available under: doi: 10.1002/cphc.200800081

Zusammenfassung

Thiols have a strong tendency to be chemisorbed to gold surfaces forming self-assembled monolayers. The feature of strong S-Au bond formation has been exploited in numerous applications including the immobilisation of DNA on gold surfaces for the generation of DNA microarrays or gold electrodes for measuring charge migration mediated by double stranded DNA. To be immobilised on gold, DNA has to be modified with thiol functionalities. Usually, for this purpose oligonucleotides are equipped with thioalkyl moieties at the 5 - or 3 -terminus. These modifications have been employed in studies dedicated to directly measure electrical transport through DNA molecules.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
530 Physik

Schlagwörter

DNA, fluorescence, immobilisation, nucleoside, thiol gold interaction

Konferenz

Rezension
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Forschungsvorhaben

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ISO 690BORNEMANN, Benjamin, Shoupeng LIU, Artur ERBE, Elke SCHEER, Andreas MARX, 2008. Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces. In: ChemPhysChem. 2008, 9(9), pp. 1241-1244. Available under: doi: 10.1002/cphc.200800081
BibTex
@article{Bornemann2008Thiol-9344,
  year={2008},
  doi={10.1002/cphc.200800081},
  title={Thiolated Nucleotides for Immobilisation of DNA Oligomers on Gold Surfaces},
  number={9},
  volume={9},
  journal={ChemPhysChem},
  pages={1241--1244},
  author={Bornemann, Benjamin and Liu, Shoupeng and Erbe, Artur and Scheer, Elke and Marx, Andreas}
}
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