Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein

Kurzanzeige
dc.contributor.authorRobotta, Marta
dc.contributor.authorBraun, Patrick
dc.contributor.authorSubramaniam, Vinod
dc.contributor.authorHuber, Martinadeu
dc.contributor.authorDrescher, Malte
dc.contributor.authorRooijen, Bart D. vandeu
dc.date.accessioned2011-11-29T07:23:32Zdeu
dc.date.available2012-02-29T23:25:05Zdeu
dc.date.issued2011-02-07
dc.description.abstractThe physiologically relevant conformation of membrane-bound α-Synuclein (αS) can be either a horseshoe or an extended helix structure. Experimental data obtained by site-directed spin labeling in combination with pulsed electron paramagnetic resonance provide compelling evidence of the coexistence of the horseshoe structure and an extended helix of αS bound to a membrane surface, and potentially resolve the debate on the structure of membrane-bound αS.eng
dc.description.versionpublished
dc.identifier.citationFirst publ. in: ChemPhysChem ; 12 (2011), 2. - S. 267-269deu
dc.identifier.doi10.1002/cphc.201000815deu
dc.identifier.pmid21275016
dc.identifier.ppn353818445deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/16109
dc.language.isoengdeu
dc.legacy.dateIssued2011-11-29deu
dc.rightsterms-of-usedeu
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/deu
dc.subjectelectron paramagnetic resonancedeu
dc.subjectmembranesdeu
dc.subjectproteinsdeu
dc.subjectsite-directed spin labelingdeu
dc.subjectvesiclesdeu
dc.subject.ddc540deu
dc.titleDirect Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synucleineng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
kops.citation.bibtex
@article{Robotta2011-02-07Direc-16109,
  year={2011},
  doi={10.1002/cphc.201000815},
  title={Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein},
  number={2},
  volume={12},
  issn={1439-4235},
  journal={ChemPhysChem},
  pages={267--269},
  author={Robotta, Marta and Braun, Patrick and Subramaniam, Vinod and Huber, Martina and Drescher, Malte and Rooijen, Bart D. van}
}
kops.citation.iso690ROBOTTA, Marta, Patrick BRAUN, Vinod SUBRAMANIAM, Martina HUBER, Malte DRESCHER, Bart D. van ROOIJEN, 2011. Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein. In: ChemPhysChem. 2011, 12(2), pp. 267-269. ISSN 1439-4235. eISSN 1439-7641. Available under: doi: 10.1002/cphc.201000815deu
kops.citation.iso690ROBOTTA, Marta, Patrick BRAUN, Vinod SUBRAMANIAM, Martina HUBER, Malte DRESCHER, Bart D. van ROOIJEN, 2011. Direct Evidence of Coexisting Horseshoe and Extended Helix Conformations of Membrane-Bound Alpha-Synuclein. In: ChemPhysChem. 2011, 12(2), pp. 267-269. ISSN 1439-4235. eISSN 1439-7641. Available under: doi: 10.1002/cphc.201000815eng
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