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A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers

A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers

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BARNABE, Alexandra, Karine GAMACHE, João Vitor Paes DE CAMARGO, Erin ALLEN-FLANAGAN, Mathilde RIOUX, Jens PRUESSNER, Marco LEYTON, Karim NADER, 2022. A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers. In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. Springer Nature. ISSN 0893-133X. eISSN 1740-634X. Available under: doi: 10.1038/s41386-022-01455-6

@article{Barnabe2022-09-29novel-58741, title={A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers}, year={2022}, doi={10.1038/s41386-022-01455-6}, issn={0893-133X}, journal={Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology}, author={Barnabe, Alexandra and Gamache, Karine and de Camargo, João Vitor Paes and Allen-Flanagan, Erin and Rioux, Mathilde and Pruessner, Jens and Leyton, Marco and Nader, Karim} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/58741"> <dc:contributor>Leyton, Marco</dc:contributor> <dc:contributor>Pruessner, Jens</dc:contributor> <dc:contributor>de Camargo, João Vitor Paes</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:title>A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers</dcterms:title> <dc:creator>Rioux, Mathilde</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Barnabe, Alexandra</dc:creator> <dcterms:abstract xml:lang="eng">Tobacco use is the leading cause of preventable mortality worldwide. Since current smoking cessation aids show only modest efficacy, new interventions are needed. Given the evidence that stress is a potent trigger for smoking, the present randomized clinical trial tested whether stress could augment the effects of a memory updating (retrieval-extinction) intervention. Non-treatment seeking smokers (n = 76) were assigned to one of four conditions composed of either a stressful or non-stressful psychosocial challenge followed by either smoking or neutral cues. Ten minutes after this manipulation, all underwent a 60-minute extinction procedure during which they viewed smoking-related videos and images and manipulated smoking paraphernalia. Compared to participants who were not exposed to the laboratory stressor, the stressor-exposed groups exhibited greater psychophysiological responses during their intervention and greater decreases in cigarette use at two- and six-weeks follow-up independent of smoking cue exposure. Together, these findings suggest that the ability of stress to activate cigarette seeking processes can be exploited to decrease cigarette use. With replication, the stress-based intervention could become a novel strategy for decreasing cigarette use in non-treatment seeking smokers.Clinicaltrials.gov identifier: NCT04843969.</dcterms:abstract> <dc:creator>Pruessner, Jens</dc:creator> <dc:contributor>Rioux, Mathilde</dc:contributor> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-10-06T09:12:16Z</dc:date> <dc:creator>Leyton, Marco</dc:creator> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/58741"/> <dcterms:issued>2022-09-29</dcterms:issued> <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/> <dc:creator>Nader, Karim</dc:creator> <dc:rights>Attribution 4.0 International</dc:rights> <dc:creator>Gamache, Karine</dc:creator> <dc:creator>Allen-Flanagan, Erin</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-10-06T09:12:16Z</dcterms:available> <dc:contributor>Allen-Flanagan, Erin</dc:contributor> <dc:creator>de Camargo, João Vitor Paes</dc:creator> <dc:contributor>Nader, Karim</dc:contributor> <dc:contributor>Gamache, Karine</dc:contributor> <dc:language>eng</dc:language> <dc:contributor>Barnabe, Alexandra</dc:contributor> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> </rdf:Description> </rdf:RDF>

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