Chemistry of fungal meroterpenoid cyclases

Barra, Lena; Abe, Ikuro

Chemistry of fungal meroterpenoid cyclases

Dateien

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Datum

2021

Autor:innen

Barra, Lena

Abe, Ikuro

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Natural Product Reports. Royal Society of Chemistry (RSC). 2021, 38(3), pp. 566-585. ISSN 0265-0568. eISSN 1460-4752. Available under: doi: 10.1039/D0NP00056F

Zusammenfassung

ungal meroterpenoid cyclases are a recently discovered emerging family of membrane-integrated, non-canonical terpene cyclases. They catalyze the conversion of hybrid isoprenic precursors towards complex scaffolds and are therefore of great importance in the structure diversification in meroterpenoid biosynthesis. The products of these pathways exhibit intriguing molecular scaffolds and highly potent bioactivities, making them privileged structures from Nature and attractive candidates for drug development or industrial applications. This review will provide a comprehensive and comparative view on fungal meroterpenoid cyclases, their intriguing chemistries and importance for the scaffold formation step towards polycyclic meroterpenoid natural products.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

BARRA, Lena, Ikuro ABE, 2021. Chemistry of fungal meroterpenoid cyclases. In: Natural Product Reports. Royal Society of Chemistry (RSC). 2021, 38(3), pp. 566-585. ISSN 0265-0568. eISSN 1460-4752. Available under: doi: 10.1039/D0NP00056F

BibTex

@article{Barra2021Chemi-57548,
  year={2021},
  doi={10.1039/D0NP00056F},
  title={Chemistry of fungal meroterpenoid cyclases},
  number={3},
  volume={38},
  issn={0265-0568},
  journal={Natural Product Reports},
  pages={566--585},
  author={Barra, Lena and Abe, Ikuro}
}

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