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Does physical activity reduce the risk of psychosis? : a systematic review and meta-analysis of prospective studies

Does physical activity reduce the risk of psychosis? : a systematic review and meta-analysis of prospective studies

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BROKMEIER, Luisa Leonie, Joseph FIRTH, Davy VANCAMPFORT, Lee SMITH, Jeroen DEENIK, Simon ROSENBAUM, Brendon STUBBS, Felipe Barreto SCHUCH, 2020. Does physical activity reduce the risk of psychosis? : a systematic review and meta-analysis of prospective studies. In: Psychiatry research. Elsevier. 284, 112675. ISSN 0165-1781. eISSN 1872-7123. Available under: doi: 10.1016/j.psychres.2019.112675

@article{Brokmeier2020-02physi-49195, title={Does physical activity reduce the risk of psychosis? : a systematic review and meta-analysis of prospective studies}, year={2020}, doi={10.1016/j.psychres.2019.112675}, volume={284}, issn={0165-1781}, journal={Psychiatry research}, author={Brokmeier, Luisa Leonie and Firth, Joseph and Vancampfort, Davy and Smith, Lee and Deenik, Jeroen and Rosenbaum, Simon and Stubbs, Brendon and Schuch, Felipe Barreto}, note={Article Number: 112675} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/49195"> <dc:creator>Smith, Lee</dc:creator> <dc:contributor>Firth, Joseph</dc:contributor> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Vancampfort, Davy</dc:contributor> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:creator>Stubbs, Brendon</dc:creator> <dc:creator>Firth, Joseph</dc:creator> <dc:contributor>Stubbs, Brendon</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-04-03T09:29:45Z</dcterms:available> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:creator>Schuch, Felipe Barreto</dc:creator> <dcterms:issued>2020-02</dcterms:issued> <dc:creator>Vancampfort, Davy</dc:creator> <dcterms:abstract xml:lang="eng">Longitudinal prospective cohorts have suggested that physical activity (PA) may be a protective factor against psychosis and schizophrenia. However, no meta-analysis has been conducted. The study aims to examine the prospective relationship between PA and incident psychosis/schizophrenia. Major databases were searched from inception to July 2019 for prospective studies that calculated the odds ratio (OR) or the adjusted odds ratio (AOR) of incident psychosis/schizophrenia in people with higher PA against people with lower PA. Methodological quality was assessed using the Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was conducted, for OR and AOR, separately. Across 4 cohorts (N = 30,025 median males = 50%, median follow-up = 32 years), people with high self-reported PA (versus low PA) were at reduced odds of developing psychosis/schizophrenia (OR = 0.73, 95%CI 0.532 to 0.995, p = 0.047). Analysis including 2 cohorts presenting AOR were not statistically significant (AOR = 0.59, 95%CI 0.253 to 1.383, p = 0.226). Overall study quality was high (mean NOS = 7.0). The literature on the topic is scarce, whilst crude analysis suggests that PA may be a protective factor against the emergence of psychosis/schizophrenia, but when adjusting for covariates, the association is no longer significant. Further studies with objective physical activity and adjustment for confounders are needed.</dcterms:abstract> <dc:contributor>Deenik, Jeroen</dc:contributor> <dc:language>eng</dc:language> <dc:creator>Rosenbaum, Simon</dc:creator> <dc:contributor>Rosenbaum, Simon</dc:contributor> <dc:contributor>Schuch, Felipe Barreto</dc:contributor> <dc:contributor>Brokmeier, Luisa Leonie</dc:contributor> <dc:creator>Deenik, Jeroen</dc:creator> <dc:creator>Brokmeier, Luisa Leonie</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-04-03T09:29:45Z</dc:date> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/49195"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Smith, Lee</dc:contributor> <dcterms:title>Does physical activity reduce the risk of psychosis? : a systematic review and meta-analysis of prospective studies</dcterms:title> </rdf:Description> </rdf:RDF>

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