Type of Publication: | Journal article |
Publication status: | Published |
URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1cbyeyen2k6ez5 |
Author: | Schartl, Manfred; Kneitz, Susanne; Volkoff, Helene; Adolfi, Mateus; Schmidt, Cornelia; Fischer, Petra; Minx, Patrick; Tomlinson, Chad; Meyer, Axel; Warren, Wesley C. |
Year of publication: | 2019 |
Published in: | Genome biology and evolution ; 11 (2019), 8. - pp. 2099-2106. - eISSN 1759-6653 |
Pubmed ID: | 31282935 |
DOI (citable link): | https://dx.doi.org/10.1093/gbe/evz139 |
Summary: |
The piranha enjoys notoriety due to its infamous predatory behavior but much is still not understood about its evolutionary origins and the underlying molecular mechanisms for its unusual feeding biology. We sequenced and assembled the red-bellied piranha (Pygocentrus nattereri) genome to aid future phenotypic and genetic investigations. The assembled draft genome is similar to other related fishes in repeat composition and gene count. Our evaluation of genes under positive selection suggests candidates for adaptations of piranhas' feeding behavior in neural functions, behavior and regulation of energy metabolism. In the fasted brain, we find genes differentially expressed that are involved in lipid metabolism and appetite regulation as well as genes that may control the aggression/boldness behavior of hungry piranhas. Our first analysis of the piranha genome offers new insight and resources for the study of piranha biology and for feeding motivation and starvation in other organisms.
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Subject (DDC): | 570 Biosciences, Biology |
Keywords: | whole genome sequencing, genome annotation, comparative genomics, RNA-seq transcriptome, energy homeostasis, starvation |
Link to License: | Attribution 4.0 International |
Bibliography of Konstanz: | Yes |
Refereed: | Yes |
SCHARTL, Manfred, Susanne KNEITZ, Helene VOLKOFF, Mateus ADOLFI, Cornelia SCHMIDT, Petra FISCHER, Patrick MINX, Chad TOMLINSON, Axel MEYER, Wesley C. WARREN, 2019. The piranha draft genome provides molecular insight associated to its unique feeding behavior. In: Genome biology and evolution. 11(8), pp. 2099-2106. eISSN 1759-6653. Available under: doi: 10.1093/gbe/evz139
@article{Schartl2019-08-01piran-46415, title={The piranha draft genome provides molecular insight associated to its unique feeding behavior}, year={2019}, doi={10.1093/gbe/evz139}, number={8}, volume={11}, journal={Genome biology and evolution}, pages={2099--2106}, author={Schartl, Manfred and Kneitz, Susanne and Volkoff, Helene and Adolfi, Mateus and Schmidt, Cornelia and Fischer, Petra and Minx, Patrick and Tomlinson, Chad and Meyer, Axel and Warren, Wesley C.} }
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