The influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients
| Type of Publication: | Journal article |
| Publication status: | Published |
| Author: | Kirsch, Peter; Ronshausen, S.; Mier, Daniela; Gallhofer, Bernd |
| Year of publication: | 2007 |
| Published in: | Pharmacopsychiatry ; 40 (2007), 5. - pp. 196-198. - ISSN 0176-3679. - eISSN 1439-0795 |
| Pubmed ID: | 17874350 |
| DOI (citable link): | https://dx.doi.org/10.1055/s-2007-984463 |
| Summary: |
Neuroleptic dysphoria is discussed as a serious side effect of antipsychotic medication. One aspect of this condition, a reduced motivation to reach potential rewards, might be induced by a blockade of striatal D2 receptors resulting in a reduced reactivity of the brain reward system. However, since this D2 antagonistic effect is higher for typical than atypical antipsychotics, typical antipsychotics should induce a stronger dampening of brain reward system activation. This hypothesis was tested in an event related functional magnetic resonance imaging study.
|
| Subject (DDC): | 150 Psychology |
| Refereed: | Yes |
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KIRSCH, Peter, S. RONSHAUSEN, Daniela MIER, Bernd GALLHOFER, 2007. The influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients. In: Pharmacopsychiatry. 40(5), pp. 196-198. ISSN 0176-3679. eISSN 1439-0795. Available under: doi: 10.1055/s-2007-984463
@article{Kirsch2007-09influ-45682, title={The influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients}, year={2007}, doi={10.1055/s-2007-984463}, number={5}, volume={40}, issn={0176-3679}, journal={Pharmacopsychiatry}, pages={196--198}, author={Kirsch, Peter and Ronshausen, S. and Mier, Daniela and Gallhofer, Bernd} }
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