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Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design

Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design

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Prüfsumme: MD5:e33627851a1119b248d0fbc1913b394f

SUMMERER, Daniel, Nicolas Z. RUDINGER, Ilka DETMER, Andreas MARX, 2005. Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design. In: Angewandte Chemie International Edition. 44(30), pp. 4712-4715. ISSN 1433-7851

@article{Summerer2005-07-25Enhan-452, title={Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design}, year={2005}, doi={10.1002/anie.200500047}, number={30}, volume={44}, issn={1433-7851}, journal={Angewandte Chemie International Edition}, pages={4712--4715}, author={Summerer, Daniel and Rudinger, Nicolas Z. and Detmer, Ilka and Marx, Andreas} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/452"> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> <dc:contributor>Rudinger, Nicolas Z.</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-20T14:43:21Z</dcterms:available> <dc:contributor>Marx, Andreas</dc:contributor> <dc:contributor>Detmer, Ilka</dc:contributor> <dc:format>application/pdf</dc:format> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/452"/> <dc:language>eng</dc:language> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-20T14:43:21Z</dc:date> <dcterms:title>Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design</dcterms:title> <dcterms:issued>2005-07-25</dcterms:issued> <dc:creator>Marx, Andreas</dc:creator> <dcterms:abstract xml:lang="eng">How is a selective enzyme made even more selective? With a combinatorial approach to redesign an enzyme motif the mismatch extension selectivity of DNA polymerases was increased. The results impart new and deeper insight into the mechanisms of DNA polymerases and provide new tools for applications such as efficient genotyping.</dcterms:abstract> <dc:creator>Rudinger, Nicolas Z.</dc:creator> <dcterms:bibliographicCitation>First publ. in: Angewandte Chemie International Edition 44 (2005), 30, pp. 4712-4715</dcterms:bibliographicCitation> <dc:rights>deposit-license</dc:rights> <dc:creator>Detmer, Ilka</dc:creator> <dc:creator>Summerer, Daniel</dc:creator> <dc:contributor>Summerer, Daniel</dc:contributor> </rdf:Description> </rdf:RDF>

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