KOPS - The Institutional Repository of the University of Konstanz

Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design

Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design

Cite This

Files in this item

Checksum: MD5:e33627851a1119b248d0fbc1913b394f

SUMMERER, Daniel, Nicolas Z. RUDINGER, Ilka DETMER, Andreas MARX, 2005. Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design. In: Angewandte Chemie International Edition. 44(30), pp. 4712-4715. ISSN 1433-7851. Available under: doi: 10.1002/anie.200500047

@article{Summerer2005-07-25Enhan-452, title={Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design}, year={2005}, doi={10.1002/anie.200500047}, number={30}, volume={44}, issn={1433-7851}, journal={Angewandte Chemie International Edition}, pages={4712--4715}, author={Summerer, Daniel and Rudinger, Nicolas Z. and Detmer, Ilka and Marx, Andreas} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/452"> <dc:rights>terms-of-use</dc:rights> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/452/1/Summerer_Marx.pdf"/> <dc:contributor>Rudinger, Nicolas Z.</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-20T14:43:21Z</dcterms:available> <dc:contributor>Marx, Andreas</dc:contributor> <dc:contributor>Detmer, Ilka</dc:contributor> <dc:format>application/pdf</dc:format> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/452"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:language>eng</dc:language> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-20T14:43:21Z</dc:date> <dcterms:title>Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design</dcterms:title> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/452/1/Summerer_Marx.pdf"/> <dcterms:issued>2005-07-25</dcterms:issued> <dc:creator>Marx, Andreas</dc:creator> <dc:creator>Rudinger, Nicolas Z.</dc:creator> <dcterms:abstract xml:lang="eng">How is a selective enzyme made even more selective? With a combinatorial approach to redesign an enzyme motif the mismatch extension selectivity of DNA polymerases was increased. The results impart new and deeper insight into the mechanisms of DNA polymerases and provide new tools for applications such as efficient genotyping.</dcterms:abstract> <dcterms:bibliographicCitation>First publ. in: Angewandte Chemie International Edition 44 (2005), 30, pp. 4712-4715</dcterms:bibliographicCitation> <dc:creator>Detmer, Ilka</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:creator>Summerer, Daniel</dc:creator> <dc:contributor>Summerer, Daniel</dc:contributor> </rdf:Description> </rdf:RDF>

Downloads since Oct 1, 2014 (Information about access statistics)

Summerer_Marx.pdf 1065

This item appears in the following Collection(s)

Search KOPS


Browse

My Account