New Approaches to Control Infections : Anti-biofilm Strategies against Gram-negative Bacteria
| Type of Publication: | Journal article |
| Publication status: | Published |
| Author: | Sommer, Roman; Joachim, Ines; Wagner, Stefanie; Titz, Alexander |
| Year of publication: | 2013 |
| Published in: | CHIMIA : International Journal for Chemistry ; 67 (2013), 4. - pp. 286-290. - ISSN 0009-4293 |
| DOI (citable link): | https://dx.doi.org/10.2533/chimia.2013.286 |
| Summary: |
Hospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.
|
| Subject (DDC): | 540 Chemistry |
| Bibliography of Konstanz: | Yes |
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SOMMER, Roman, Ines JOACHIM, Stefanie WAGNER, Alexander TITZ, 2013. New Approaches to Control Infections : Anti-biofilm Strategies against Gram-negative Bacteria. In: CHIMIA : International Journal for Chemistry. 67(4), pp. 286-290. ISSN 0009-4293. Available under: doi: 10.2533/chimia.2013.286
@article{Sommer2013-04-24Appro-41909, title={New Approaches to Control Infections : Anti-biofilm Strategies against Gram-negative Bacteria}, year={2013}, doi={10.2533/chimia.2013.286}, number={4}, volume={67}, issn={0009-4293}, journal={CHIMIA : International Journal for Chemistry}, pages={286--290}, author={Sommer, Roman and Joachim, Ines and Wagner, Stefanie and Titz, Alexander} }
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