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Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds

Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds

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AL-MASOUDI, Najim A., Niran J. AL-SALIHI, Yossra A. MARICH, Timo MARKUS, 2016. Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds. In: Journal of Fluorescence. 26(1), pp. 31-35. ISSN 1053-0509. eISSN 1573-4994

@article{Al-Masoudi2016Synth-39824, title={Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds}, year={2016}, doi={10.1007/s10895-015-1695-x}, number={1}, volume={26}, issn={1053-0509}, journal={Journal of Fluorescence}, pages={31--35}, author={Al-Masoudi, Najim A. and Al-Salihi, Niran J. and Marich, Yossra A. and Markus, Timo} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/39824"> <dcterms:issued>2016</dcterms:issued> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/39824"/> <dc:contributor>Al-Masoudi, Najim A.</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-08-10T09:36:57Z</dcterms:available> <dc:language>eng</dc:language> <dc:contributor>Markus, Timo</dc:contributor> <dc:creator>Marich, Yossra A.</dc:creator> <dcterms:title>Synthesis and Fluorescence Properties of new Monastrol Analogs Conjugated Fluorescent Coumarin Scaffolds</dcterms:title> <dc:creator>Markus, Timo</dc:creator> <dc:contributor>Al-Salihi, Niran J.</dc:contributor> <dc:contributor>Marich, Yossra A.</dc:contributor> <dc:creator>Al-Masoudi, Najim A.</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-08-10T09:36:57Z</dc:date> <dc:creator>Al-Salihi, Niran J.</dc:creator> <dcterms:abstract xml:lang="eng">A mild and efficient method has been used for the synthesis of ethyl 4-(3-hydroxphenyl)-6-methyl-2-thioxo-1,3-dihydroprimidine-5-carboxylate (monastrol) (2), via Biginelli reaction. Alkylation of 2 with the fluorescent coumarin 3 afforded the new thioether analog 4. Similarly, ethyl 4-(6,8-dichloro-2-oxo-2 H-chromen-3-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylate (6) was prepared. The synthesized compounds are fluorescent active and show wavelength of maximum absorption (λmax) in UV or visible region in MeOH at room temperature.</dcterms:abstract> </rdf:Description> </rdf:RDF>

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