Publikation: Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV
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2013
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Organic Letters. 2013, 15(21), pp. 5472-5475. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol4026217
Zusammenfassung
An enantioselective gram-scale synthesis of one of the most potent SIRT1-inhibitors has been accomplished by an unprecedented domino reaction sequence establishing the cyclohepta[b]indole core. This method was developed for application in natural product synthesis of a variety of indole alkaloids.
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GRITSCH, Philipp, Erik STEMPEL, Tanja GAICH, 2013. Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV. In: Organic Letters. 2013, 15(21), pp. 5472-5475. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol4026217BibTex
@article{Gritsch2013-11Enant-38333,
year={2013},
doi={10.1021/ol4026217},
title={Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV},
number={21},
volume={15},
issn={1523-7060},
journal={Organic Letters},
pages={5472--5475},
author={Gritsch, Philipp and Stempel, Erik and Gaich, Tanja}
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