KOPS - Das Institutionelle Repositorium der Universität Konstanz

Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa

Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:149bf16e61111145801780df9e70c019

SZAMOSVÁRI, Dávid, Valentin F. REICHLE, Monica JURESCHI, Thomas BÖTTCHER, 2016. Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa. In: Chemical Communications : ChemComm. 52(92), pp. 13440-13443. ISSN 0009-241X. eISSN 1364-548X

@article{Szamosvari2016Synth-37585, title={Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa}, year={2016}, doi={10.1039/c6cc06295d}, number={92}, volume={52}, issn={0009-241X}, journal={Chemical Communications : ChemComm}, pages={13440--13443}, author={Szamosvári, Dávid and Reichle, Valentin F. and Jureschi, Monica and Böttcher, Thomas} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/37585"> <dc:creator>Jureschi, Monica</dc:creator> <dc:contributor>Jureschi, Monica</dc:contributor> <dc:contributor>Böttcher, Thomas</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-02-17T14:29:15Z</dc:date> <dcterms:title>Synthetic quinolone signal analogues inhibiting the virulence factor elastase of Pseudomonas aeruginosa</dcterms:title> <dc:creator>Szamosvári, Dávid</dc:creator> <dc:language>eng</dc:language> <dcterms:issued>2016</dcterms:issued> <dc:contributor>Szamosvári, Dávid</dc:contributor> <dc:creator>Reichle, Valentin F.</dc:creator> <dcterms:abstract xml:lang="eng">We explore the chemical space of Pseudomonas quinolone signal analogs as privileged structures and report the discovery of a thioquinolone as a potent inhibitor of the important virulence factor elastase of the human pathogen Pseudomonas aeruginosa. We provide evidence that the derivative binds to the active site zinc of elastase and additionally acts as a fluorescent zinc sensor.</dcterms:abstract> <dcterms:rights rdf:resource="http://nbn-resolving.de/urn:nbn:de:bsz:352-20150914100631302-4485392-8"/> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/37585"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-02-17T14:29:15Z</dcterms:available> <dc:creator>Böttcher, Thomas</dc:creator> <dc:contributor>Reichle, Valentin F.</dc:contributor> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 17.02.2017 (Informationen über die Zugriffsstatistik)

Szamosvari_0-373507.pdf 20

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto