Aufgrund von Vorbereitungen auf eine neue Version von KOPS, können kommenden Montag und Dienstag keine Publikationen eingereicht werden. (Due to preparations for a new version of KOPS, no publications can be submitted next Monday and Tuesday.)
Type of Publication: | Journal article |
Publication status: | Published |
Author: | Schlotz, Nina; Roulin, Anne; Ebert, Dieter; Martin-Creuzburg, Dominik |
Year of publication: | 2016 |
Published in: | Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology ; 201 (2016). - pp. 115-123. - ISSN 1095-6433. - eISSN 1531-4332 |
Pubmed ID: | 27421236 |
DOI (citable link): | https://dx.doi.org/10.1016/j.cbpa.2016.07.008 |
Summary: |
Eicosanoids derive from essential polyunsaturated fatty acids (PUFA) and play crucial roles in immunity, development, and reproduction. However, potential links between dietary PUFA supply and eicosanoid biosynthesis are poorly understood, especially in invertebrates. Using Daphnia magna and its bacterial parasite Pasteuria ramosa as model system, we studied the expression of genes coding for key enzymes in eicosanoid biosynthesis and of genes related to oogenesis in response to dietary arachidonic acid and eicosapentaenoic acid in parasite-exposed and non-exposed animals. Gene expression related to cyclooxygenase activity was especially responsive to the dietary PUFA supply and parasite challenge, indicating a role for prostanoid eicosanoids in immunity and reproduction. Vitellogenin gene expression was induced upon parasite exposure in all food treatments, suggesting infection-related interference with the host's reproductive system. Our findings highlight the potential of dietary PUFA to modulate the expression of key enzymes involved in eicosanoid biosynthesis and reproduction and thus underpin the idea that the dietary PUFA supply can influence invertebrate immune functions and host-parasite interactions.
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Subject (DDC): | 570 Biosciences, Biology |
Keywords: | Arachidonic acid; Cyclooxygenase; Daphnia magna; Eicosapentaenoic acid; Food quality; Host-parasite interactions; Pasteuria ramosa; Vitellogenin |
Bibliography of Konstanz: | Yes |
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SCHLOTZ, Nina, Anne ROULIN, Dieter EBERT, Dominik MARTIN-CREUZBURG, 2016. Combined effects of dietary polyunsaturated fatty acids and parasite exposure on eicosanoid-related gene expression in an invertebrate model. In: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 201, pp. 115-123. ISSN 1095-6433. eISSN 1531-4332. Available under: doi: 10.1016/j.cbpa.2016.07.008
@article{Schlotz2016Combi-37542, title={Combined effects of dietary polyunsaturated fatty acids and parasite exposure on eicosanoid-related gene expression in an invertebrate model}, year={2016}, doi={10.1016/j.cbpa.2016.07.008}, volume={201}, issn={1095-6433}, journal={Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology}, pages={115--123}, author={Schlotz, Nina and Roulin, Anne and Ebert, Dieter and Martin-Creuzburg, Dominik} }
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