KOPS - Das Institutionelle Repositorium der Universität Konstanz

A mass spectrometry-based hybrid method for structural modeling of protein complexes

A mass spectrometry-based hybrid method for structural modeling of protein complexes

Zitieren

Dateien zu dieser Ressource

Dateien Größe Format Anzeige

Zu diesem Dokument gibt es keine Dateien.

POLITIS, Argyris, Florian STENGEL, Zoe HALL, Helena HERNÁNDEZ, Alexander LEITNER, Thomas WALZTHOENI, Carol V. ROBINSON, Ruedi AEBERSOLD, 2014. A mass spectrometry-based hybrid method for structural modeling of protein complexes. In: Nature Methods. 11(4), pp. 403-406. ISSN 1548-7091. eISSN 1548-7105

@article{Politis2014spect-33030, title={A mass spectrometry-based hybrid method for structural modeling of protein complexes}, year={2014}, doi={10.1038/nmeth.2841}, number={4}, volume={11}, issn={1548-7091}, journal={Nature Methods}, pages={403--406}, author={Politis, Argyris and Stengel, Florian and Hall, Zoe and Hernández, Helena and Leitner, Alexander and Walzthoeni, Thomas and Robinson, Carol V. and Aebersold, Ruedi} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/33030"> <dc:contributor>Stengel, Florian</dc:contributor> <dcterms:issued>2014</dcterms:issued> <dc:contributor>Hall, Zoe</dc:contributor> <dc:creator>Leitner, Alexander</dc:creator> <dcterms:abstract xml:lang="eng">We describe a method that integrates data derived from different mass spectrometry (MS)-based techniques with a modeling strategy for structural characterization of protein assemblies. We encoded structural data derived from native MS, bottom-up proteomics, ion mobility-MS and chemical cross-linking MS into modeling restraints to compute the most likely structure of a protein assembly. We used the method to generate near-native models for three known structures and characterized an assembly intermediate of the proteasomal base.</dcterms:abstract> <dc:contributor>Politis, Argyris</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-02-18T10:37:20Z</dc:date> <dc:contributor>Aebersold, Ruedi</dc:contributor> <dcterms:title>A mass spectrometry-based hybrid method for structural modeling of protein complexes</dcterms:title> <dc:creator>Robinson, Carol V.</dc:creator> <dc:contributor>Walzthoeni, Thomas</dc:contributor> <dc:creator>Hernández, Helena</dc:creator> <dc:creator>Hall, Zoe</dc:creator> <dc:language>eng</dc:language> <dc:creator>Aebersold, Ruedi</dc:creator> <dc:creator>Politis, Argyris</dc:creator> <dc:creator>Stengel, Florian</dc:creator> <dc:contributor>Leitner, Alexander</dc:contributor> <dc:contributor>Robinson, Carol V.</dc:contributor> <dc:contributor>Hernández, Helena</dc:contributor> <dc:creator>Walzthoeni, Thomas</dc:creator> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/33030"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-02-18T10:37:20Z</dcterms:available> </rdf:Description> </rdf:RDF>

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto