Publikation:

Toxicology : a discipline in need of academic anchoring ; the point of view of the German Society of Toxicology

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Datum

2015

Autor:innen

Gundert-Remy, Ursula
Barth, Holger
Degen, Gisela H.
Landsiedel, Robert

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Archives of Toxicology. 2015, 89(10), pp. 1881-1893. ISSN 0340-5761. eISSN 1432-0738. Available under: doi: 10.1007/s00204-015-1577-7

Zusammenfassung

The paper describes the importance of toxicology as a discipline, its past achievements, current scientific challenges, and future development. Toxicological expertise is instrumental in the reduction of human health risks arising from chemicals and drugs. Toxicological assessment is needed to evaluate evidence and arguments, whether or not there is a scientific base for concern. The immense success already achieved by toxicological work is exemplified by reduced pollution of air, soil, water, and safer working places. Predominantly predictive toxicological testing is derived from the findings to assess risks to humans and the environment. Assessment of the adversity of molecular effects (including epigenetic effects), the effects of mixtures, and integration of exposure and biokinetics into in vitro testing are emerging challenges for toxicology. Toxicology is a translational science with its base in fundamental science. Academic institutions play an essential part by providing scientific innovation and education of young scientists.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Toxicology, Translational science, Academia, In silico toxicology, In vitro toxicology, Omics, Regulatory toxicology

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ISO 690GUNDERT-REMY, Ursula, Holger BARTH, Alexander BÜRKLE, Gisela H. DEGEN, Robert LANDSIEDEL, 2015. Toxicology : a discipline in need of academic anchoring ; the point of view of the German Society of Toxicology. In: Archives of Toxicology. 2015, 89(10), pp. 1881-1893. ISSN 0340-5761. eISSN 1432-0738. Available under: doi: 10.1007/s00204-015-1577-7
BibTex
@article{GundertRemy2015Toxic-33280,
  year={2015},
  doi={10.1007/s00204-015-1577-7},
  title={Toxicology : a discipline in need of academic anchoring ; the point of view of the German Society of Toxicology},
  number={10},
  volume={89},
  issn={0340-5761},
  journal={Archives of Toxicology},
  pages={1881--1893},
  author={Gundert-Remy, Ursula and Barth, Holger and Bürkle, Alexander and Degen, Gisela H. and Landsiedel, Robert}
}
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