A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen

Schlotz, Nina; Pester, Michael; Freese, Heike M.; Martin-Creuzburg, Dominik

A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen

Dateien

Schlotz_259738.pdf(1.02 MB)

Datum

2014

Publikationstyp

Zeitschriftenartikel

Erschienen in

FEMS Microbiology Ecology ; 90 (2014), 2. - S. 467-477. - ISSN 0168-6496. - eISSN 1574-6941

Zusammenfassung

A dietary deficiency in polyunsaturated fatty acids (PUFAs) and/or sterols can severely constrain growth and reproduction of invertebrate consumers. Single nutrients are potentially assigned to different physiological processes, for example to support defence mechanisms; therefore, lipid requirements of healthy and pathogen-challenged consumers might differ. In an oral exposure experiment, we explored the effects of dietary PUFAs and cholesterol on growth, reproduction and survival of an aquatic key herbivore (Daphnia magna) exposed to an opportunistic pathogen (Pseudomonas sp.). We show that healthy and pathogen-challenged D. magna are strongly albeit differentially affected by the biochemical composition of their food sources. Supplementation of a C20 PUFA-deficient diet with arachidonic acid (ARA) resulted in increased survival and reproduction of pathogen-challenged D. magna. We propose that the observed benefit of consuming an ARA-rich diet during pathogen challenge is conveyed partially via ARA-derived eicosanoids. This study is one of the first to consider the importance of dietary PUFAs in modifying fitness parameters of pathogen-challenged invertebrate hosts. Our results suggest that dietary PUFA supply should receive increased attention in host–microorganisms interactions and invertebrate disease models to better understand and predict disease dynamics in natural populations

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

food quality; gut pathogen; host resistance; intestinal microbiology.

Zitieren

ISO 690

SCHLOTZ, Nina, Michael PESTER, Heike M. FREESE, Dominik MARTIN-CREUZBURG, 2014. A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen. In: FEMS Microbiology Ecology. 90(2), pp. 467-477. ISSN 0168-6496. eISSN 1574-6941. Available under: doi: 10.1111/1574-6941.12407

BibTex

@article{Schlotz2014dieta-29418,
  year={2014},
  doi={10.1111/1574-6941.12407},
  title={A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen},
  number={2},
  volume={90},
  issn={0168-6496},
  journal={FEMS Microbiology Ecology},
  pages={467--477},
  author={Schlotz, Nina and Pester, Michael and Freese, Heike M. and Martin-Creuzburg, Dominik}
}

RDF

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29418">
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:abstract xml:lang="eng">A dietary deficiency in polyunsaturated fatty acids (PUFAs) and/or sterols can severely constrain growth and reproduction of invertebrate consumers. Single nutrients are potentially assigned to different physiological processes, for example to support defence mechanisms; therefore, lipid requirements of healthy and pathogen-challenged consumers might differ. In an oral exposure experiment, we explored the effects of dietary PUFAs and cholesterol on growth, reproduction and survival of an aquatic key herbivore (Daphnia magna) exposed to an opportunistic pathogen (Pseudomonas sp.). We show that healthy and pathogen-challenged D. magna are strongly albeit differentially affected by the biochemical composition of their food sources. Supplementation of a C20 PUFA-deficient diet with arachidonic acid (ARA) resulted in increased survival and reproduction of pathogen-challenged D. magna. We propose that the observed benefit of consuming an ARA-rich diet during pathogen challenge is conveyed partially via ARA-derived eicosanoids. This study is one of the first to consider the importance of dietary PUFAs in modifying fitness parameters of pathogen-challenged invertebrate hosts. Our results suggest that dietary PUFA supply should receive increased attention in host–microorganisms interactions and invertebrate disease models to better understand and predict disease dynamics in natural populations</dcterms:abstract>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/29418/3/Schlotz_259738.pdf"/>
    <dcterms:title>A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen</dcterms:title>
    <dc:language>eng</dc:language>
    <dc:contributor>Freese, Heike M.</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dc:creator>Martin-Creuzburg, Dominik</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/29418"/>
    <dcterms:issued>2014</dcterms:issued>
    <dc:contributor>Pester, Michael</dc:contributor>
    <dc:creator>Freese, Heike M.</dc:creator>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Schlotz, Nina</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-12-10T15:05:23Z</dcterms:available>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Martin-Creuzburg, Dominik</dc:contributor>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/29418/3/Schlotz_259738.pdf"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2014-12-10T15:05:23Z</dc:date>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Schlotz, Nina</dc:contributor>
    <dc:creator>Pester, Michael</dc:creator>
  </rdf:Description>
</rdf:RDF>

Universitätsbibliographie

Ja