Interaction of membrane-spanning proteins with peripheral and lipid-anchored membrane proteins : perspectives from protein-lipid interactions (Review)

Loading...
Thumbnail Image
Date
2002
Authors
Marsh, Derek
Horváth, László I.
Swamy, Musti. J.
Mantripragada, Sankaram
Editors
Contact
Journal ISSN
Electronic ISSN
ISBN
Bibliographical data
Publisher
Series
DOI (citable link)
ArXiv-ID
International patent number
EU project number
Project
Open Access publication
Collections
Restricted until
Title in another language
Research Projects
Organizational Units
Journal Issue
Publication type
Journal article
Publication status
Published in
Molecular Membrane Biology ; 19 (2002), 4. - pp. 247-255. - ISSN 0968-7688. - eISSN 1464-5203
Abstract
Studies of lipid-protein interactions in double-reconstituted systems involving both integral and peripheral or lipid-anchored proteins are reviewed. Membranes of dimyristoyl phosphatidylglycerol containing either myelin proteolipid protein or cytochrome c oxidase were studied. The partner peripheral proteins bound to these membranes were myelin basic protein or cytochrome c, respectively. In addition, the interactions between the myelin proteolipid protein and avidin that was membraneanchored by binding to N-biotinyl phosphatidylethanolamine were studied in dimyristoyl phosphatidylcholine membranes. Steric exclusion plays a significant role when sizes of the peripheral protein and transmembrane domain of the integral protein are comparable. Even so, the effects on avidin-linked lipids are different from those induced by myelin basic protein on freely diffusible lipids, both interacting with the myelin proteolipid protein. Both the former and the cytochrome c/cytochrome oxidase couple evidence a propagation of lipid perturbation out from the intramembrane protein interface that could be a basis for formation of microdomains.
Summary in another language
Subject (DDC)
570 Biosciences, Biology
Keywords
Lipid-protein interactions,spin labels,electron spin resonance,myelin proteins,cytochrome oxidase
Conference
Review
undefined / . - undefined, undefined. - (undefined; undefined)
Cite This
ISO 690MARSH, Derek, László I. HORVÁTH, Musti. J. SWAMY, Sankaram MANTRIPRAGADA, Jörg KLEINSCHMIDT, 2002. Interaction of membrane-spanning proteins with peripheral and lipid-anchored membrane proteins : perspectives from protein-lipid interactions (Review). In: Molecular Membrane Biology. 19(4), pp. 247-255. ISSN 0968-7688. eISSN 1464-5203. Available under: doi: 10.1080/09687680210162419
BibTex
@article{Marsh2002Inter-7268,
  year={2002},
  doi={10.1080/09687680210162419},
  title={Interaction of membrane-spanning proteins with peripheral and lipid-anchored membrane proteins : perspectives from protein-lipid interactions (Review)},
  number={4},
  volume={19},
  issn={0968-7688},
  journal={Molecular Membrane Biology},
  pages={247--255},
  author={Marsh, Derek and Horváth, László I. and Swamy, Musti. J. and Mantripragada, Sankaram and Kleinschmidt, Jörg}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/7268">
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7268"/>
    <dc:creator>Marsh, Derek</dc:creator>
    <dc:contributor>Kleinschmidt, Jörg</dc:contributor>
    <dcterms:issued>2002</dcterms:issued>
    <dcterms:title>Interaction of membrane-spanning proteins with peripheral and lipid-anchored membrane proteins : perspectives from protein-lipid interactions (Review)</dcterms:title>
    <dcterms:abstract xml:lang="eng">Studies of lipid-protein interactions in double-reconstituted systems involving both integral and peripheral or lipid-anchored proteins are reviewed. Membranes of dimyristoyl phosphatidylglycerol containing either myelin proteolipid protein or cytochrome c oxidase were studied. The partner peripheral proteins bound to these membranes were myelin basic protein or cytochrome c, respectively. In addition, the interactions between the myelin proteolipid protein and avidin that was membraneanchored by binding to N-biotinyl phosphatidylethanolamine were studied in dimyristoyl phosphatidylcholine membranes. Steric exclusion plays a significant role when sizes of the peripheral protein and transmembrane domain of the integral protein are comparable. Even so, the effects on avidin-linked lipids are different from those induced by myelin basic protein on freely diffusible lipids, both interacting with the myelin proteolipid protein. Both the former and the cytochrome c/cytochrome oxidase couple evidence a propagation of lipid perturbation out from the intramembrane protein interface that could be a basis for formation of microdomains.</dcterms:abstract>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Marsh, Derek</dc:contributor>
    <dc:creator>Mantripragada, Sankaram</dc:creator>
    <dc:creator>Swamy, Musti. J.</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7268/1/Interaction_of_membrane_spanning_proteins_with_peripheral_and_lipid_anchored_membrane_proteins.pdf"/>
    <dcterms:bibliographicCitation>Molecular Membrane Biology ; 19 (2002). - S. 247-255</dcterms:bibliographicCitation>
    <dc:contributor>Mantripragada, Sankaram</dc:contributor>
    <dc:creator>Kleinschmidt, Jörg</dc:creator>
    <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Swamy, Musti. J.</dc:contributor>
    <dc:contributor>Horváth, László I.</dc:contributor>
    <dc:language>eng</dc:language>
    <dc:creator>Horváth, László I.</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:33:06Z</dc:date>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7268/1/Interaction_of_membrane_spanning_proteins_with_peripheral_and_lipid_anchored_membrane_proteins.pdf"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:33:06Z</dcterms:available>
    <dc:format>application/pdf</dc:format>
  </rdf:Description>
</rdf:RDF>
Internal note
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Contact
URL of original publication
Test date of URL
Examination date of dissertation
Method of financing
Comment on publication
Alliance license
Corresponding Authors der Uni Konstanz vorhanden
International Co-Authors
Bibliography of Konstanz
No
Refereed