Adverse childhood experiences and autonomic regulation in response to acute stress : the role of the sympathetic and parasympathetic nervous systems

Winzeler, Katja; Voellmin, Annette; Hug, Evelin; Kirmse, Ursula; Helmig, Simone; Princip, Mary; Cajochen, Christian; Bader, Klaus; Wilhelm, Frank H.

Adverse childhood experiences and autonomic regulation in response to acute stress : the role of the sympathetic and parasympathetic nervous systems

Dateien

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Datum

2017

Autor:innen

Winzeler, Katja

Voellmin, Annette

Hug, Evelin

Kirmse, Ursula

Helmig, Simone

Princip, Mary

Cajochen, Christian

Bader, Klaus

Wilhelm, Frank H.

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Psychologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Anxiety, Stress, & Coping. 2017, 30(2), pp. 145-154. ISSN 1061-5806. eISSN 1477-2205. Available under: doi: 10.1080/10615806.2016.1238076

Zusammenfassung

Background and objectives: After a previous report demonstrated blunted heart rate (HR) reactivity in association with adverse childhood experiences (ACEs) [Voellmin, A., Winzeler, K., Hug, E., Wilhelm, F. H., Schaefer, V., Gaab, J., … Bader, K. (2015). Blunted endocrine and cardiovascular reactivity in young healthy women reporting a history of childhood adversity. Psychoneuroendocrinology, 51, 58–67. doi:10.1016/j.psyneuen.2014.09.008], the present analysis aimed at clarifying the role of the sympathetic and parasympathetic branches of the autonomic nervous system in this relationship.

Design and Methods: One hundred eighteen healthy young women provided data on ACEs and underwent psychosocial stress testing. Systolic blood pressure (SBP) and respiratory sinus arrhythmia (RSA, quantified by high-frequency HR variability) were assessed as measures of sympathetic and parasympathetic cardiovascular activity, respectively. A mediation model was calculated to test the indirect effects of ACEs on HR via SBP and RSA.

Results: The effect of ACEs on HR reactivity was mediated by SBP reactivity but not by RSA reactivity. ACEs were associated with reduced SBP at rest.

Conclusions: ACEs were associated with down-regulation in a measure of sympathetic but no alteration in a measure of parasympathetic cardiovascular stress reactivity in adulthood. Future research will need to clarify whether this indicates risk or resilience.

Fachgebiet (DDC)

150 Psychologie

Zitieren

ISO 690

WINZELER, Katja, Annette VOELLMIN, Evelin HUG, Ursula KIRMSE, Simone HELMIG, Mary PRINCIP, Christian CAJOCHEN, Klaus BADER, Frank H. WILHELM, 2017. Adverse childhood experiences and autonomic regulation in response to acute stress : the role of the sympathetic and parasympathetic nervous systems. In: Anxiety, Stress, & Coping. 2017, 30(2), pp. 145-154. ISSN 1061-5806. eISSN 1477-2205. Available under: doi: 10.1080/10615806.2016.1238076

BibTex

@article{Winzeler2017-03-04Adver-39123,
  year={2017},
  doi={10.1080/10615806.2016.1238076},
  title={Adverse childhood experiences and autonomic regulation in response to acute stress : the role of the sympathetic and parasympathetic nervous systems},
  number={2},
  volume={30},
  issn={1061-5806},
  journal={Anxiety, Stress, & Coping},
  pages={145--154},
  author={Winzeler, Katja and Voellmin, Annette and Hug, Evelin and Kirmse, Ursula and Helmig, Simone and Princip, Mary and Cajochen, Christian and Bader, Klaus and Wilhelm, Frank H.}
}

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    <dcterms:abstract xml:lang="eng">Background and objectives: After a previous report demonstrated blunted heart rate (HR) reactivity in association with adverse childhood experiences (ACEs) [Voellmin, A., Winzeler, K., Hug, E., Wilhelm, F. H., Schaefer, V., Gaab, J., … Bader, K. (2015). Blunted endocrine and cardiovascular reactivity in young healthy women reporting a history of childhood adversity. Psychoneuroendocrinology, 51, 58–67. doi:10.1016/j.psyneuen.2014.09.008], the present analysis aimed at clarifying the role of the sympathetic and parasympathetic branches of the autonomic nervous system in this relationship.&lt;br /&gt;&lt;br /&gt;Design and Methods: One hundred eighteen healthy young women provided data on ACEs and underwent psychosocial stress testing. Systolic blood pressure (SBP) and respiratory sinus arrhythmia (RSA, quantified by high-frequency HR variability) were assessed as measures of sympathetic and parasympathetic cardiovascular activity, respectively. A mediation model was calculated to test the indirect effects of ACEs on HR via SBP and RSA.&lt;br /&gt;&lt;br /&gt;Results: The effect of ACEs on HR reactivity was mediated by SBP reactivity but not by RSA reactivity. ACEs were associated with reduced SBP at rest.&lt;br /&gt;&lt;br /&gt;Conclusions: ACEs were associated with down-regulation in a measure of sympathetic but no alteration in a measure of parasympathetic cardiovascular stress reactivity in adulthood. Future research will need to clarify whether this indicates risk or resilience.</dcterms:abstract>
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