Nitroimidazoles Part 7 : Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives
| dc.contributor.author | Al-Masoudi, Najim A. | deu |
| dc.contributor.author | Pfleiderer, Wolfgang | |
| dc.contributor.author | Pannecouque, Christophe | deu |
| dc.date.accessioned | 2013-05-06T13:31:30Z | deu |
| dc.date.available | 2013-05-06T13:31:30Z | deu |
| dc.date.issued | 2012 | |
| dc.description.abstract | Reverse transcriptase enzyme (RT) is an attractive target for the development of new drugs useful in AIDS therapy and HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs), and offers the possibility of generating structures of increased potency. On this basis, a series of 4-oxo-3-phenyl-2-(phenylimino)thiazolidin-5-ylidene, 3-hydroxypropyl, 3-azidopropyl, and 3-aminopropyl derivatives of 1-benzyl-2-ethyl-4-nitroimidazoles 6–8, as well as the substituted 1,2,3-triazolo analogs 12–14, the diazepam 15 and carboxamide derivatives 16 and 17 were synthesized. All compounds have been evaluated for their anti-HIV activity. | eng |
| dc.description.version | published | |
| dc.identifier.citation | Zeitschrift für Naturforschung B ; 67b (2012), 8. - S. 835-842 | deu |
| dc.identifier.doi | 10.5560/ZNB.2012-0122 | deu |
| dc.identifier.uri | http://kops.uni-konstanz.de/handle/123456789/22647 | |
| dc.language.iso | eng | deu |
| dc.legacy.dateIssued | 2013-05-06 | deu |
| dc.rights | terms-of-use | deu |
| dc.rights.uri | https://rightsstatements.org/page/InC/1.0/ | deu |
| dc.subject | Anti-HIV activity | deu |
| dc.subject | Nitroimidazoles | deu |
| dc.subject | NNRTIs | deu |
| dc.subject | Piperazine Derivatives | deu |
| dc.subject.ddc | 540 | deu |
| dc.title | Nitroimidazoles Part 7 : Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives | eng |
| dc.type | JOURNAL_ARTICLE | deu |
| dspace.entity.type | Publication | |
| kops.citation.bibtex | @article{AlMasoudi2012Nitro-22647,
year={2012},
doi={10.5560/ZNB.2012-0122},
title={Nitroimidazoles Part 7 : Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives},
number={8},
volume={67},
issn={1865-7117},
journal={Zeitschrift für Naturforschung B},
author={Al-Masoudi, Najim A. and Pfleiderer, Wolfgang and Pannecouque, Christophe}
} | |
| kops.citation.iso690 | AL-MASOUDI, Najim A., Wolfgang PFLEIDERER, Christophe PANNECOUQUE, 2012. Nitroimidazoles Part 7 : Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives. In: Zeitschrift für Naturforschung B. 2012, 67(8). ISSN 1865-7117. Available under: doi: 10.5560/ZNB.2012-0122 | deu |
| kops.citation.iso690 | AL-MASOUDI, Najim A., Wolfgang PFLEIDERER, Christophe PANNECOUQUE, 2012. Nitroimidazoles Part 7 : Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives. In: Zeitschrift für Naturforschung B. 2012, 67(8). ISSN 1865-7117. Available under: doi: 10.5560/ZNB.2012-0122 | eng |
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| kops.identifier.nbn | urn:nbn:de:bsz:352-226477 | deu |
| kops.sourcefield | Zeitschrift für Naturforschung B. 2012, <b>67</b>(8). ISSN 1865-7117. Available under: doi: 10.5560/ZNB.2012-0122 | deu |
| kops.sourcefield.plain | Zeitschrift für Naturforschung B. 2012, 67(8). ISSN 1865-7117. Available under: doi: 10.5560/ZNB.2012-0122 | deu |
| kops.sourcefield.plain | Zeitschrift für Naturforschung B. 2012, 67(8). ISSN 1865-7117. Available under: doi: 10.5560/ZNB.2012-0122 | eng |
| kops.submitter.email | oleg.kozlov@uni-konstanz.de | deu |
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| source.bibliographicInfo.issue | 8 | |
| source.bibliographicInfo.volume | 67 | |
| source.identifier.issn | 1865-7117 | |
| source.periodicalTitle | Zeitschrift für Naturforschung B |
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