Cobalt mediated intramolecular [2+2+2]-cycloaddition of enediynes ­towards linear annelated polycycles

Eckenberg, Peter; Groth, Ulrich

Cobalt mediated intramolecular [2+2+2]-cycloaddition of enediynes towards linear annelated polycycles

Dateien

Cobalt_mediated_intramolecular.pdfGröße: 98.76 KBDownloads: 580

Datum

2003

Autor:innen

Eckenberg, Peter

Groth, Ulrich

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Synlett. 2003, 23(14), pp. 2188-2192. ISSN 0570-0833. eISSN 1521-3773. Available under: doi: 10.1002/anie.198405393

Zusammenfassung

The cobalt mediated [2+2+2]-cycloaddition of enediynes 13 and 18 affords linear annelated polycycles such as the hexahydro naphthalene 14 and the decahydro anthracene 19. This latter compound can be transformed into the enantiomerically pure anthracene derivative 21 in only two reaction steps. 1,9,10-Trihydroxy octahydro anthracene (21) represents the ABC-framework of many anthracycline antibiotics such as the antitumor active daunomycine.

Fachgebiet (DDC)

540 Chemie

Schlagwörter

[2+2+2]-cycloaddition, enediynes, annelated polycycles

Zitieren

ISO 690

ECKENBERG, Peter, Ulrich GROTH, 2003. Cobalt mediated intramolecular [2+2+2]-cycloaddition of enediynes towards linear annelated polycycles. In: Synlett. 2003, 23(14), pp. 2188-2192. ISSN 0570-0833. eISSN 1521-3773. Available under: doi: 10.1002/anie.198405393

BibTex

@article{Eckenberg2003Cobal-9632,
  year={2003},
  doi={10.1002/anie.198405393},
  title={Cobalt mediated intramolecular [2+2+2]-cycloaddition of enediynes towards linear annelated polycycles},
  number={14},
  volume={23},
  issn={0570-0833},
  journal={Synlett},
  pages={2188--2192},
  author={Eckenberg, Peter and Groth, Ulrich}
}

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Universitätsbibliographie

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