Publikation:

No PTSD-related differences in diurnal cortisol profiles of genocide survivors

Lade...
Vorschaubild

Dateien

KolassaNo.pdf
KolassaNo.pdfGröße: 4.77 MBDownloads: 884

Datum

2009

Autor:innen

Eckart, Cindy
Engler, Harald
Riether, Carsten
Kolassa, Stephan
Elbert, Thomas
Kolassa, Iris-Tatjana

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Stress and trauma-associated immunological changes and their implications on health
Open Access-Veröffentlichung
Open Access Green
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Psychoneuroendocrinology. 2009, 34(4), pp. 523-531. Available under: doi: 10.1016/j.psyneuen.2008.10.012

Zusammenfassung

Posttraumatic stress disorder (PTSD) has been associated with reduced cortisol levels. Opposing results have been interpreted as resulting from methodological differences between studies.We investigated the diurnal profile of salivary cortisol in a population of highly traumatized adult males from Rwanda with and without PTSD, who spent the whole day of examination together under amaximally standardized schedule. Besides the detection of PTSDrelated alterations in cortisol release we aimed at determining physiologically relevant effects of cumulative trauma exposure on HPA functioning in interaction with or independent of diagnosis. There were no differences in the diurnal pattern of cortisol release between subjects with and without PTSD. We observed an increasing prevalence of PTSD with increasing number of different traumatic event types experienced, replicating earlier results on a building-block effect of multiple traumatization. However, size of cumulative exposure was not related to any of the cortisol measures. The results suggest that besides methodological constraints also confounding factors not previously controlled for, e.g., sex differences or current life stress, might contribute to the diverging results of lowered, unchanged or enhanced cortisol secretion in PTSD. Future research should therefore closely monitor these possible confounds to optimize models for cortisol in research on stress-dependent illnesses.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
150 Psychologie

Schlagwörter

Cortisol, HPA axis, Posttraumatic stress disorder, PTSD, Stress, Building-block effect

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690ECKART, Cindy, Harald ENGLER, Carsten RIETHER, Stephan KOLASSA, Thomas ELBERT, Iris-Tatjana KOLASSA, 2009. No PTSD-related differences in diurnal cortisol profiles of genocide survivors. In: Psychoneuroendocrinology. 2009, 34(4), pp. 523-531. Available under: doi: 10.1016/j.psyneuen.2008.10.012
BibTex
@article{Eckart2009PTSDr-10998,
  year={2009},
  doi={10.1016/j.psyneuen.2008.10.012},
  title={No PTSD-related differences in diurnal cortisol profiles of genocide survivors},
  number={4},
  volume={34},
  journal={Psychoneuroendocrinology},
  pages={523--531},
  author={Eckart, Cindy and Engler, Harald and Riether, Carsten and Kolassa, Stephan and Elbert, Thomas and Kolassa, Iris-Tatjana}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/10998">
    <dc:contributor>Kolassa, Stephan</dc:contributor>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/10998"/>
    <dc:creator>Kolassa, Stephan</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dc:creator>Engler, Harald</dc:creator>
    <dcterms:title>No PTSD-related differences in diurnal cortisol profiles of genocide survivors</dcterms:title>
    <dcterms:bibliographicCitation>First publ. in: Psychoneuroendocrinology ; 34 (2009), 4. - S. 523-531</dcterms:bibliographicCitation>
    <dc:contributor>Kolassa, Iris-Tatjana</dc:contributor>
    <dc:creator>Kolassa, Iris-Tatjana</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:creator>Elbert, Thomas</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:24:37Z</dcterms:available>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dc:contributor>Riether, Carsten</dc:contributor>
    <dc:creator>Riether, Carsten</dc:creator>
    <dc:contributor>Elbert, Thomas</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10998/1/KolassaNo.pdf"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:rights>terms-of-use</dc:rights>
    <dc:contributor>Eckart, Cindy</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:contributor>Engler, Harald</dc:contributor>
    <dcterms:abstract xml:lang="eng">Posttraumatic stress disorder (PTSD) has been associated with reduced cortisol levels. Opposing results have been interpreted as resulting from methodological differences between studies.We investigated the diurnal profile of salivary cortisol in a population of highly traumatized adult males from Rwanda with and without PTSD, who spent the whole day of examination together under amaximally standardized schedule. Besides the detection of PTSDrelated alterations in cortisol release we aimed at determining physiologically relevant effects of cumulative trauma exposure on HPA functioning in interaction with or independent of diagnosis. There were no differences in the diurnal pattern of cortisol release between subjects with and without PTSD. We observed an increasing prevalence of PTSD with increasing number of different traumatic event types experienced, replicating earlier results on a   building-block effect   of multiple traumatization. However, size of cumulative exposure was not related to any of the cortisol measures. The results suggest that besides methodological constraints also confounding factors not previously controlled for, e.g., sex differences or current life stress, might contribute to the diverging results of lowered, unchanged or enhanced cortisol secretion in PTSD. Future research should therefore closely monitor these possible confounds to optimize models for cortisol in research on stress-dependent illnesses.</dcterms:abstract>
    <dc:creator>Eckart, Cindy</dc:creator>
    <dc:format>application/pdf</dc:format>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:24:37Z</dc:date>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10998/1/KolassaNo.pdf"/>
    <dcterms:issued>2009</dcterms:issued>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen