Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus

Lade...
Vorschaubild
Dateien
Mock_0-394571.pdf
Mock_0-394571.pdfGröße: 2.28 MBDownloads: 488
Datum
2017
Autor:innen
Mock, Thomas
Otillar, Robert P.
Strauss, Jan
McMullan, Mark
Paajanen, Pirita
Schmutz, Jeremy
Salamov, Asaf
Sanges, Remo
et al.
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Hybrid
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Zusammenfassung

The Southern Ocean houses a diverse and productive community of organisms. Unicellular eukaryotic diatoms are the main primary producers in this environment, where photosynthesis is limited by low concentrations of dissolved iron and large seasonal fluctuations in light, temperature and the extent of sea ice. How diatoms have adapted to this extreme environment is largely unknown. Here we present insights into the genome evolution of a cold-adapted diatom from the Southern Ocean, Fragilariopsis cylindrus, based on a comparison with temperate diatoms. We find that approximately 24.7 per cent of the diploid F. cylindrus genome consists of genetic loci with alleles that are highly divergent (15.1 megabases of the total genome size of 61.1 megabases). These divergent alleles were differentially expressed across environmental conditions, including darkness, low iron, freezing, elevated temperature and increased CO2. Alleles with the largest ratio of non-synonymous to synonymous nucleotide substitutions also show the most pronounced condition-dependent expression, suggesting a correlation between diversifying selection and allelic differentiation. Divergent alleles may be involved in adaptation to environmental fluctuations in the Southern Ocean.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690MOCK, Thomas, Robert P. OTILLAR, Jan STRAUSS, Mark MCMULLAN, Pirita PAAJANEN, Jeremy SCHMUTZ, Asaf SALAMOV, Remo SANGES, Ansgar GRUBER, Peter G. KROTH, 2017. Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus. In: Nature. 2017, 541(7638), pp. 536-540. ISSN 0028-0836. eISSN 1476-4687. Available under: doi: 10.1038/nature20803
BibTex
@article{Mock2017-01-16Evolu-37359,
  year={2017},
  doi={10.1038/nature20803},
  title={Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus},
  number={7638},
  volume={541},
  issn={0028-0836},
  journal={Nature},
  pages={536--540},
  author={Mock, Thomas and Otillar, Robert P. and Strauss, Jan and McMullan, Mark and Paajanen, Pirita and Schmutz, Jeremy and Salamov, Asaf and Sanges, Remo and Gruber, Ansgar and Kroth, Peter G.}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/37359">
    <dc:creator>Mock, Thomas</dc:creator>
    <dc:creator>Strauss, Jan</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-02-13T13:47:59Z</dcterms:available>
    <dc:contributor>Otillar, Robert P.</dc:contributor>
    <dc:contributor>Paajanen, Pirita</dc:contributor>
    <dc:contributor>Mock, Thomas</dc:contributor>
    <dcterms:abstract xml:lang="eng">The Southern Ocean houses a diverse and productive community of organisms. Unicellular eukaryotic diatoms are the main primary producers in this environment, where photosynthesis is limited by low concentrations of dissolved iron and large seasonal fluctuations in light, temperature and the extent of sea ice. How diatoms have adapted to this extreme environment is largely unknown. Here we present insights into the genome evolution of a cold-adapted diatom from the Southern Ocean, Fragilariopsis cylindrus, based on a comparison with temperate diatoms. We find that approximately 24.7 per cent of the diploid F. cylindrus genome consists of genetic loci with alleles that are highly divergent (15.1 megabases of the total genome size of 61.1 megabases). These divergent alleles were differentially expressed across environmental conditions, including darkness, low iron, freezing, elevated temperature and increased CO2. Alleles with the largest ratio of non-synonymous to synonymous nucleotide substitutions also show the most pronounced condition-dependent expression, suggesting a correlation between diversifying selection and allelic differentiation. Divergent alleles may be involved in adaptation to environmental fluctuations in the Southern Ocean.</dcterms:abstract>
    <dc:contributor>Kroth, Peter G.</dc:contributor>
    <dc:contributor>Schmutz, Jeremy</dc:contributor>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dc:creator>Salamov, Asaf</dc:creator>
    <dc:contributor>Strauss, Jan</dc:contributor>
    <dcterms:title>Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus</dcterms:title>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Sanges, Remo</dc:creator>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/37359"/>
    <dc:creator>Kroth, Peter G.</dc:creator>
    <dc:contributor>McMullan, Mark</dc:contributor>
    <dc:contributor>Gruber, Ansgar</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Salamov, Asaf</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/37359/1/Mock_0-394571.pdf"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Paajanen, Pirita</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/37359/1/Mock_0-394571.pdf"/>
    <dc:contributor>Sanges, Remo</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-02-13T13:47:59Z</dc:date>
    <dc:creator>Schmutz, Jeremy</dc:creator>
    <dc:language>eng</dc:language>
    <dc:creator>McMullan, Mark</dc:creator>
    <dcterms:issued>2017-01-16</dcterms:issued>
    <dc:creator>Otillar, Robert P.</dc:creator>
    <dc:creator>Gruber, Ansgar</dc:creator>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen