Publikation: p63 Adjusts Sugar Taste of Epidermal Layers
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2017
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Journal of Investigative Dermatology. Elsevier. 2017, 137(6), pp. 1204-1206. ISSN 0022-202X. eISSN 1523-1747. Available under: doi: 10.1016/j.jid.2017.02.967
Zusammenfassung
p63 is a master regulator of epidermal biology, sustaining stemness and renewal capacity of the proliferating keratinocyte compartment. Hamanaka and Mutlu propose that p63 regulates the keratinocyte proliferation/differentiation switch by affecting the cellular glycolic rate through a direct transcriptional regulation of the metabolic enzyme PFKFB3. This finding sheds light on mechanisms underlining p63 function in the skin and suggests a role for energetic metabolism in epidermal biology.
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570 Biowissenschaften, Biologie
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AMELIO, Ivano, Gerry MELINO, Eleonora CANDI, 2017. p63 Adjusts Sugar Taste of Epidermal Layers. In: Journal of Investigative Dermatology. Elsevier. 2017, 137(6), pp. 1204-1206. ISSN 0022-202X. eISSN 1523-1747. Available under: doi: 10.1016/j.jid.2017.02.967BibTex
@article{Amelio2017Adjus-56686,
year={2017},
doi={10.1016/j.jid.2017.02.967},
title={p63 Adjusts Sugar Taste of Epidermal Layers},
number={6},
volume={137},
issn={0022-202X},
journal={Journal of Investigative Dermatology},
pages={1204--1206},
author={Amelio, Ivano and Melino, Gerry and Candi, Eleonora}
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<dcterms:abstract xml:lang="eng">p63 is a master regulator of epidermal biology, sustaining stemness and renewal capacity of the proliferating keratinocyte compartment. Hamanaka and Mutlu propose that p63 regulates the keratinocyte proliferation/differentiation switch by affecting the cellular glycolic rate through a direct transcriptional regulation of the metabolic enzyme PFKFB3. This finding sheds light on mechanisms underlining p63 function in the skin and suggests a role for energetic metabolism in epidermal biology.</dcterms:abstract>
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