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p63 Adjusts Sugar Taste of Epidermal Layers

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2017

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Melino, Gerry
Candi, Eleonora

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Journal of Investigative Dermatology. Elsevier. 2017, 137(6), pp. 1204-1206. ISSN 0022-202X. eISSN 1523-1747. Available under: doi: 10.1016/j.jid.2017.02.967

Zusammenfassung

p63 is a master regulator of epidermal biology, sustaining stemness and renewal capacity of the proliferating keratinocyte compartment. Hamanaka and Mutlu propose that p63 regulates the keratinocyte proliferation/differentiation switch by affecting the cellular glycolic rate through a direct transcriptional regulation of the metabolic enzyme PFKFB3. This finding sheds light on mechanisms underlining p63 function in the skin and suggests a role for energetic metabolism in epidermal biology.

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570 Biowissenschaften, Biologie

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ISO 690AMELIO, Ivano, Gerry MELINO, Eleonora CANDI, 2017. p63 Adjusts Sugar Taste of Epidermal Layers. In: Journal of Investigative Dermatology. Elsevier. 2017, 137(6), pp. 1204-1206. ISSN 0022-202X. eISSN 1523-1747. Available under: doi: 10.1016/j.jid.2017.02.967
BibTex
@article{Amelio2017Adjus-56686,
  year={2017},
  doi={10.1016/j.jid.2017.02.967},
  title={p63 Adjusts Sugar Taste of Epidermal Layers},
  number={6},
  volume={137},
  issn={0022-202X},
  journal={Journal of Investigative Dermatology},
  pages={1204--1206},
  author={Amelio, Ivano and Melino, Gerry and Candi, Eleonora}
}
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