Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation

dc.contributor.authorJunker, Astrid
dc.contributor.authorRohn, Hendrik
dc.contributor.authorCzauderna, Tobias
dc.contributor.authorKlukas, Christian
dc.contributor.authorHartmann, Anja
dc.contributor.authorSchreiber, Falk
dc.date.accessioned2017-04-03T09:07:20Z
dc.date.available2017-04-03T09:07:20Z
dc.date.issued2012-03-01eng
dc.description.abstractThe Systems Biology Graphical Notation (SBGN) is an emerging standard for the uniform representation of biological processes and networks. By using examples from gene regulation and metabolism, this protocol shows the construction of SBGN maps by either manual drawing or automatic translation using the tool SBGN-ED. In addition, it discusses the enrichment of SBGN maps with different kinds of -omics data to bring numerical data into the context of these networks in order to facilitate the interpretation of experimental data. Finally, the export of such maps to public websites, including clickable images, supports the communication of results within the scientific community. With regard to the described functionalities, other tools partially overlap with SBGN-ED. However, currently, SBGN-ED is the only tool that combines all of these functions, including the representation in SBGN, data mapping and website export. This protocol aims to assist scientists with the step-by-step procedure, which altogether takes ∼90 min.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1038/nprot.2012.002eng
dc.identifier.pmid22383037eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/38265
dc.language.isoengeng
dc.subject.ddc004eng
dc.titleCreating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notationeng
dc.typeJOURNAL_ARTICLEeng
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@article{Junker2012-03-01Creat-38265,
  year={2012},
  doi={10.1038/nprot.2012.002},
  title={Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation},
  number={3},
  volume={7},
  issn={1754-2189},
  journal={Nature Protocols},
  pages={579--593},
  author={Junker, Astrid and Rohn, Hendrik and Czauderna, Tobias and Klukas, Christian and Hartmann, Anja and Schreiber, Falk}
}
kops.citation.iso690JUNKER, Astrid, Hendrik ROHN, Tobias CZAUDERNA, Christian KLUKAS, Anja HARTMANN, Falk SCHREIBER, 2012. Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation. In: Nature Protocols. 2012, 7(3), pp. 579-593. ISSN 1754-2189. eISSN 1750-2799. Available under: doi: 10.1038/nprot.2012.002deu
kops.citation.iso690JUNKER, Astrid, Hendrik ROHN, Tobias CZAUDERNA, Christian KLUKAS, Anja HARTMANN, Falk SCHREIBER, 2012. Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation. In: Nature Protocols. 2012, 7(3), pp. 579-593. ISSN 1754-2189. eISSN 1750-2799. Available under: doi: 10.1038/nprot.2012.002eng
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