Melting transition of oriented Li-DNA fibers submerged in ethanol solutions

dc.contributor.authorGonzález, Adrián
dc.contributor.authorWildes, Andrew R.
dc.contributor.authorMossou, Estelle
dc.contributor.authorCristiglio, Viviana
dc.contributor.authorMoiroux, Gaël
dc.contributor.authorGarden, Jean-Luc
dc.contributor.authorCuesta-López, Santiago
dc.contributor.authorTheodorakopoulos, Nikos
dc.contributor.authorPeyrard, Michel
dc.date.accessioned2021-03-11T10:12:16Z
dc.date.available2021-03-11T10:12:16Z
dc.date.issued2021-03
dc.description.abstractThe melting transition of Li‐DNA fibers immersed in ethanol‐water solutions has been studied using calorimetry and neutron diffraction techniques. The data have been analyzed using the Peyrard‐Bishop‐Dauxois model to determine the strengths of the intra‐ and inter‐base pair potentials. The data and analysis show that the potentials are weaker than those for DNA in water. They become weaker still and the DNA less stable as the ethanol concentration increases but, conversely, the fibers become more compact and the distances between base pairs become more regular. The results show that the melting transition is relatively insensitive to local confinement and depends more on the interaction between the DNA and its aqueous environment.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1002/bip.23422eng
dc.identifier.pmid33600618eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/53133
dc.language.isoengeng
dc.subject.ddc530eng
dc.titleMelting transition of oriented Li-DNA fibers submerged in ethanol solutionseng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Gonzalez2021-03Melti-53133,
  year={2021},
  doi={10.1002/bip.23422},
  title={Melting transition of oriented Li-DNA fibers submerged in ethanol solutions},
  number={3},
  volume={112},
  issn={0006-3525},
  journal={Biopolymers},
  author={González, Adrián and Wildes, Andrew R. and Mossou, Estelle and Cristiglio, Viviana and Moiroux, Gaël and Garden, Jean-Luc and Cuesta-López, Santiago and Theodorakopoulos, Nikos and Peyrard, Michel},
  note={Article Number: e23422}
}
kops.citation.iso690GONZÁLEZ, Adrián, Andrew R. WILDES, Estelle MOSSOU, Viviana CRISTIGLIO, Gaël MOIROUX, Jean-Luc GARDEN, Santiago CUESTA-LÓPEZ, Nikos THEODORAKOPOULOS, Michel PEYRARD, 2021. Melting transition of oriented Li-DNA fibers submerged in ethanol solutions. In: Biopolymers. Wiley-Blackwell. 2021, 112(3), e23422. ISSN 0006-3525. eISSN 1097-0282. Available under: doi: 10.1002/bip.23422deu
kops.citation.iso690GONZÁLEZ, Adrián, Andrew R. WILDES, Estelle MOSSOU, Viviana CRISTIGLIO, Gaël MOIROUX, Jean-Luc GARDEN, Santiago CUESTA-LÓPEZ, Nikos THEODORAKOPOULOS, Michel PEYRARD, 2021. Melting transition of oriented Li-DNA fibers submerged in ethanol solutions. In: Biopolymers. Wiley-Blackwell. 2021, 112(3), e23422. ISSN 0006-3525. eISSN 1097-0282. Available under: doi: 10.1002/bip.23422eng
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