Stress load during childhood affects psychopathology in psychiatric patients

Lade...
Vorschaubild
Datum
2008
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
EU-Projektnummer
DFG-Projektnummer
Projekt
Open Access-Veröffentlichung
Sammlungen
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
unikn.publication.listelement.citation.prefix.version.undefined
BMC Psychiatry. 2008, 8(63). Available under: doi: 10.1186/1471-244X-8-63
Zusammenfassung

Background:
Childhood stress and trauma have been related to adult psychopathology in different psychiatric disorders. The present study aimed at verifying this relationship for stressful experiences during developmental periods by screening stress load across life in adult psychiatric inpatients with different diagnoses compared to healthy subjects. In addition, a relationship between the amount of adverse experiences and the severity of pathology, which has been described as a 'building block' effect in posttraumatic stress disorder (PTSD), was explored for nontraumatic events in psychiatric disorders other than PTSD.

Methods:
96 patients with diagnoses of Major Depressive Disorder (MDD), schizophrenia, drug addiction, or personality disorders (PD) and 31 subjects without psychiatric diagnosis were screened for adverse experiences in childhood (before the age of six years), before onset of puberty, and in adulthood using the Early Trauma Inventory and the Posttraumatic Stress Diagnostic Scale. Effects of stress load on psychopathology were examined for affective symptoms, PTSD, and severity of illness by regression analyses and comparison of subgroups with high and low stress load.

Results:
High stress load in childhood and before puberty, but not in adulthood, was related to negative affect in all participants. In patients, high stress load was related to depressive and posttraumatic symptoms, severity of disorder, and the diagnoses of MDD and PD.

Conclusion:
Results support the hypothesis of stress-sensitive periods during development, which may interact with genetic and other vulnerability factors in their influence on the progress of psychiatric disorders. A 'dose' effect of stress load on the severity of psychopathology is not restricted to the relationship between traumata and PTSD.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
150 Psychologie
Schlagwörter
Stress, Trauma, Psychiatrische Störungen, Stessbelastung in der Kindheit, Psychopathologie, Childhood stress load, Major Depressive Disorder, PTSD, Psychopathology
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690WEBER, Katja, Brigitte ROCKSTROH, Jens BORGELT, Barbara AWISZUS, Tzvetan G. POPOV, Klaus HOFFMANN, Klaus SCHONAUER, Hans WATZL, Karl PRÖPSTER, 2008. Stress load during childhood affects psychopathology in psychiatric patients. In: BMC Psychiatry. 2008, 8(63). Available under: doi: 10.1186/1471-244X-8-63
BibTex
@article{Weber2008Stres-11265,
  year={2008},
  doi={10.1186/1471-244X-8-63},
  title={Stress load during childhood affects psychopathology in psychiatric patients},
  number={63},
  volume={8},
  journal={BMC Psychiatry},
  author={Weber, Katja and Rockstroh, Brigitte and Borgelt, Jens and Awiszus, Barbara and Popov, Tzvetan G. and Hoffmann, Klaus and Schonauer, Klaus and Watzl, Hans and Pröpster, Karl}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/11265">
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/11265/1/Stress_load_during_childhood_affects_psychopathology_in_psychiatric_patients.pdf"/>
    <dc:creator>Rockstroh, Brigitte</dc:creator>
    <dc:format>application/pdf</dc:format>
    <dc:contributor>Rockstroh, Brigitte</dc:contributor>
    <dc:contributor>Pröpster, Karl</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dc:creator>Schonauer, Klaus</dc:creator>
    <dcterms:title>Stress load during childhood affects psychopathology in psychiatric patients</dcterms:title>
    <dc:language>eng</dc:language>
    <dc:creator>Awiszus, Barbara</dc:creator>
    <dc:contributor>Watzl, Hans</dc:contributor>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/11265"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/11265/1/Stress_load_during_childhood_affects_psychopathology_in_psychiatric_patients.pdf"/>
    <dcterms:bibliographicCitation>First publ. in: BMC Psychiatry 2008, 8:63</dcterms:bibliographicCitation>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:27:12Z</dc:date>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:contributor>Awiszus, Barbara</dc:contributor>
    <dc:creator>Borgelt, Jens</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:creator>Pröpster, Karl</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:creator>Watzl, Hans</dc:creator>
    <dc:creator>Weber, Katja</dc:creator>
    <dcterms:issued>2008</dcterms:issued>
    <dc:contributor>Borgelt, Jens</dc:contributor>
    <dc:contributor>Schonauer, Klaus</dc:contributor>
    <dcterms:abstract xml:lang="eng">Background:&lt;br /&gt;Childhood stress and trauma have been related to adult psychopathology in different psychiatric disorders. The present study aimed at verifying this relationship for stressful experiences during developmental periods by screening stress load across life in adult psychiatric inpatients with different diagnoses compared to healthy subjects. In addition, a relationship between the amount of adverse experiences and the severity of pathology, which has been described as a 'building block' effect in posttraumatic stress disorder (PTSD), was explored for nontraumatic events in psychiatric disorders other than PTSD.&lt;br /&gt;&lt;br /&gt;Methods:&lt;br /&gt;96 patients with diagnoses of Major Depressive Disorder (MDD), schizophrenia, drug addiction, or personality disorders (PD) and 31 subjects without psychiatric diagnosis were screened for adverse experiences in childhood (before the age of six years), before onset of puberty, and in adulthood using the Early Trauma Inventory and the Posttraumatic Stress Diagnostic Scale. Effects of stress load on psychopathology were examined for affective symptoms, PTSD, and severity of illness by regression analyses and comparison of subgroups with high and low stress load.&lt;br /&gt;&lt;br /&gt;Results:&lt;br /&gt;High stress load in childhood and before puberty, but not in adulthood, was related to negative affect in all participants. In patients, high stress load was related to depressive and posttraumatic symptoms, severity of disorder, and the diagnoses of MDD and PD.&lt;br /&gt;&lt;br /&gt;Conclusion:&lt;br /&gt;Results support the hypothesis of stress-sensitive periods during development, which may interact with genetic and other vulnerability factors in their influence on the progress of psychiatric disorders. A 'dose' effect of stress load on the severity of psychopathology is not restricted to the relationship between traumata and PTSD.</dcterms:abstract>
    <dc:contributor>Hoffmann, Klaus</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:27:12Z</dcterms:available>
    <dc:creator>Popov, Tzvetan G.</dc:creator>
    <dc:contributor>Popov, Tzvetan G.</dc:contributor>
    <dc:creator>Hoffmann, Klaus</dc:creator>
    <dc:contributor>Weber, Katja</dc:contributor>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet