Publikation:

In vivo Olefin Metathesis in Microalgae Upgrades Lipids to Building Blocks for Polymers and Chemicals

Lade...
Vorschaubild

Dateien

Schunck_2-1m03spkod7x260.pdf
Schunck_2-1m03spkod7x260.pdfGröße: 1.06 MBDownloads: 169

Datum

2022

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Hybrid
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Angewandte Chemie International Edition. Wiley. 2022, 61(44), e202211285. ISSN 1521-3773. eISSN 1521-3773. Available under: doi: 10.1002/anie.202211285

Zusammenfassung

Sustainable sources are key to future chemicals production. Microalgae are promising renewable resources as they fixate atmospheric carbon dioxide to organic molecules by photosynthesis, with sunlight as energy. Thereby they produce unsaturated fatty acids as established raw materials for the industrial production of chemical building blocks. Although these renewable feedstocks are generated inside cells, their synthetic catalytic upgrading to useful products requires ex vivo transformations. A synthetic catalysis inside living photoautotrophic cells has remained elusive. Here we show that a catalytic conversion of renewable substrates can be realized directly inside living microalgae. Organometallic catalysts are internalized and remain active inside the photoautotrophic cells, enabling in vivo catalytic olefin metathesis as new-to-nature transformation. Stored lipids are converted in vivo to alkenes and long-chain dicarboxylates as valuable building blocks for polymers. This is a key step towards the long-term goal of producing desired renewable chemicals in microalgae as living "cellular factories".

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

Catalysis, Homogeneous Catalysis, Polymers, Renewable Resources, Sustainable Chemistry

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690SCHUNCK, Natalie S., Stefan MECKING, 2022. In vivo Olefin Metathesis in Microalgae Upgrades Lipids to Building Blocks for Polymers and Chemicals. In: Angewandte Chemie International Edition. Wiley. 2022, 61(44), e202211285. ISSN 1521-3773. eISSN 1521-3773. Available under: doi: 10.1002/anie.202211285
BibTex
@article{Schunck2022-11-02Olefi-58575,
  year={2022},
  doi={10.1002/anie.202211285},
  title={In vivo Olefin Metathesis in Microalgae Upgrades Lipids to Building Blocks for Polymers and Chemicals},
  number={44},
  volume={61},
  issn={1521-3773},
  journal={Angewandte Chemie International Edition},
  author={Schunck, Natalie S. and Mecking, Stefan},
  note={Article Number: e202211285}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/58575">
    <dcterms:issued>2022-11-02</dcterms:issued>
    <dc:rights>terms-of-use</dc:rights>
    <dc:language>eng</dc:language>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-09-08T13:52:43Z</dcterms:available>
    <dc:contributor>Mecking, Stefan</dc:contributor>
    <dc:creator>Mecking, Stefan</dc:creator>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/58575/1/Schunck_2-1m03spkod7x260.pdf"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/58575/1/Schunck_2-1m03spkod7x260.pdf"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dcterms:title>In vivo Olefin Metathesis in Microalgae Upgrades Lipids to Building Blocks for Polymers and Chemicals</dcterms:title>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/58575"/>
    <dc:creator>Schunck, Natalie S.</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Schunck, Natalie S.</dc:contributor>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-09-08T13:52:43Z</dc:date>
    <dcterms:abstract xml:lang="eng">Sustainable sources are key to future chemicals production. Microalgae are promising renewable resources as they fixate atmospheric carbon dioxide to organic molecules by photosynthesis, with sunlight as energy. Thereby they produce unsaturated fatty acids as established raw materials for the industrial production of chemical building blocks. Although these renewable feedstocks are generated inside cells, their synthetic catalytic upgrading to useful products requires ex vivo transformations. A synthetic catalysis inside living photoautotrophic cells has remained elusive. Here we show that a catalytic conversion of renewable substrates can be realized directly inside living microalgae. Organometallic catalysts are internalized and remain active inside the photoautotrophic cells, enabling in vivo catalytic olefin metathesis as new-to-nature transformation. Stored lipids are converted in vivo to alkenes and long-chain dicarboxylates as valuable building blocks for polymers. This is a key step towards the long-term goal of producing desired renewable chemicals in microalgae as living "cellular factories".</dcterms:abstract>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen