Publikation: A role for a pre-T-cell receptor in T-cell development
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1993
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Boehmer, Harald von
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Immunology Today. 1993, 14(12), pp. 610-614. ISSN 0167-5699. eISSN 1355-8242. Available under: doi: 10.1016/0167-5699(93)90201-U
Zusammenfassung
Expression of a productive T-cell receptor (TCR) beta gene has profound consequences for T-cell development, preceding an increase in thymocyte number, appearance of CD4 and CD8 coreceptors and suppression of further TCR beta-gene rearrangement. Here Marcus Groettrup and Harald von Boehmer discuss the data obtained in various experimental models and describe a novel signal transducing receptor complex on pre-T cells, which may regulate the TCR beta-induced developmental changes.
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570 Biowissenschaften, Biologie
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GRÖTTRUP, Marcus, Harald von BOEHMER, 1993. A role for a pre-T-cell receptor in T-cell development. In: Immunology Today. 1993, 14(12), pp. 610-614. ISSN 0167-5699. eISSN 1355-8242. Available under: doi: 10.1016/0167-5699(93)90201-UBibTex
@article{Grottrup1993preTc-22323, year={1993}, doi={10.1016/0167-5699(93)90201-U}, title={A role for a pre-T-cell receptor in T-cell development}, number={12}, volume={14}, issn={0167-5699}, journal={Immunology Today}, pages={610--614}, author={Gröttrup, Marcus and Boehmer, Harald von} }
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