Publikation: MARK-AGE biomarkers of ageing
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2015
Autor:innen
Collino, Sebastiano
Gonos, Efstathios S.
Sikora, Ewa
Gradinaru, Daniela
Dollé, Martijn
Salmon, Michel
et al.
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Mechanisms of Ageing and Development. 2015, 151, pp. 2-12. ISSN 0047-6374. eISSN 1872-6216. Available under: doi: 10.1016/j.mad.2015.03.006
Zusammenfassung
Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation.
Zusammenfassung in einer weiteren Sprache
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570 Biowissenschaften, Biologie
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BÜRKLE, Alexander, Maria MORENO-VILLANUEVA, Sebastiano COLLINO, Efstathios S. GONOS, Ewa SIKORA, Daniela GRADINARU, Martijn DOLLÉ, Michel SALMON, 2015. MARK-AGE biomarkers of ageing. In: Mechanisms of Ageing and Development. 2015, 151, pp. 2-12. ISSN 0047-6374. eISSN 1872-6216. Available under: doi: 10.1016/j.mad.2015.03.006BibTex
@article{Burkle2015-11MARKA-31557,
year={2015},
doi={10.1016/j.mad.2015.03.006},
title={MARK-AGE biomarkers of ageing},
volume={151},
issn={0047-6374},
journal={Mechanisms of Ageing and Development},
pages={2--12},
author={Bürkle, Alexander and Moreno-Villanueva, Maria and Collino, Sebastiano and Gonos, Efstathios S. and Sikora, Ewa and Gradinaru, Daniela and Dollé, Martijn and Salmon, Michel}
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<dcterms:abstract xml:lang="eng">Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age. A plausible reason for this is the intrinsic multi-causal and multi-system nature of the ageing process. The recently completed MARK-AGE study was a large-scale integrated project supported by the European Commission. The major aim of this project was to conduct a population study comprising about 3200 subjects in order to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any marker in isolation.</dcterms:abstract>
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