Publikation:

Mechanistic Principles of Ion Transport in the Na,K-ATPase

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Apell_0-397363.pdf
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2017

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http://nbn-resolving.de/urn:nbn:de:bsz:352-0-397363
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https://doi.org/10.1134/S1023193517030028
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Russian Journal of Electrochemistry. 2017, 53(3), pp. 237-247. ISSN 1023-1935. eISSN 1608-3342. Available under: doi: 10.1134/S1023193517030028

Zusammenfassung

The Na,K-ATPase is a member of the P-type ATPase family and a primary active ion transporter for Na+ and K+ ions in the cytoplasmic membrane of virtually all animal cells. Considerable progress in understanding the ion-pump mechanism of the Na,K-ATPase was gained by combining biophysical and biochemical studies of more than 30 years with structural information at atomic resolution available since recent years. Biophysical studies have revealed detailed properties of the ion movements that led to a gated-channel model which is strongly supported by structural findings obtained for the sodium pump. The basic question how the free Gibbs energy released by ATP hydrolysis is transferred to the protein and transformed into uphill transport of the ions is still without reply.

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570 Biowissenschaften, Biologie

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ISO 690APELL, Hans-Jürgen, 2017. Mechanistic Principles of Ion Transport in the Na,K-ATPase. In: Russian Journal of Electrochemistry. 2017, 53(3), pp. 237-247. ISSN 1023-1935. eISSN 1608-3342. Available under: doi: 10.1134/S1023193517030028
BibTex
@article{Apell2017Mecha-38369,
  year={2017},
  doi={10.1134/S1023193517030028},
  title={Mechanistic Principles of Ion Transport in the Na,K-ATPase},
  number={3},
  volume={53},
  issn={1023-1935},
  journal={Russian Journal of Electrochemistry},
  pages={237--247},
  author={Apell, Hans-Jürgen},
  note={Version in Russisch erschienen in: Elektrokhimiya, 2017, Vol. 53, No. 3, pp. 270–281: МЕХАНИСТИЧЕСКИЕ ПРИНЦИПЫ ИОННОГО ТРАНСПОРТА В Na,K-АТФазе. ЭЛЕКТРОХИМИЯ}
}
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Version in Russisch erschienen in: Elektrokhimiya, 2017, Vol. 53, No. 3, pp. 270–281: МЕХАНИСТИЧЕСКИЕ ПРИНЦИПЫ ИОННОГО ТРАНСПОРТА В Na,K-АТФазе. ЭЛЕКТРОХИМИЯ
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