DGPT news: Rudolf Buchheim Award 2024

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dc.contributor.authorLambrecht, Rebekka
dc.date.accessioned2025-05-19T13:44:58Z
dc.date.available2025-05-19T13:44:58Z
dc.date.issued2025-09
dc.description.abstractThe Rudolf Buchheim Award is an annual prize awarded by the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) to recognize outstanding work from young researchers in the fields of pharmacology and toxicology. The 2025 Rudolf Buchheim Award recognizes advancements in understanding drug-induced liver injury. This year’s recipient, Rebekka Lambrecht, investigated acetaminophen (APAP)-induced liver toxicity in the lab of Prof. Thomas Brunner at the University of Konstanz. Her research highlights the role of mitochondrial damage and oxidative stress in driving hepatocyte death, revealing that metabolic reprogramming can enhance cell survival and demonstrating the mechanism APAP toxicity inhibits apoptosis and shifts cells toward necrosis. Her findings provide a deeper understanding of APAP hepatotoxicity and suggest potential therapeutic strategies aimed at stabilizing mitochondrial function and mitigating oxidative stress in drug-induced liver injury.
dc.description.versionpublisheddeu
dc.identifier.doi10.1007/s00210-025-04114-x
dc.identifier.ppn1937517071
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/73366
dc.language.isoeng
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.ddc570
dc.titleDGPT news: Rudolf Buchheim Award 2024eng
dc.typeJOURNAL_ARTICLE
dspace.entity.typePublication
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@article{Lambrecht2025-09Rudol-73366,
  title={DGPT news: Rudolf Buchheim Award 2024},
  year={2025},
  doi={10.1007/s00210-025-04114-x},
  number={9},
  volume={398},
  issn={0028-1298},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  pages={12773--12775},
  author={Lambrecht, Rebekka}
}
kops.citation.iso690LAMBRECHT, Rebekka, 2025. DGPT news: Rudolf Buchheim Award 2024. In: Naunyn-Schmiedeberg's Archives of Pharmacology. Springer. 2025, 398(9), S. 12773-12775. ISSN 0028-1298. eISSN 1432-1912. Verfügbar unter: doi: 10.1007/s00210-025-04114-xdeu
kops.citation.iso690LAMBRECHT, Rebekka, 2025. DGPT news: Rudolf Buchheim Award 2024. In: Naunyn-Schmiedeberg's Archives of Pharmacology. Springer. 2025, 398(9), pp. 12773-12775. ISSN 0028-1298. eISSN 1432-1912. Available under: doi: 10.1007/s00210-025-04114-xeng
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