Acidocalcisomes in Apicomplexan parasites

dc.contributor.authorMiranda, Kildare
dc.contributor.authorde Souza, Wanderley
dc.contributor.authorPlattner, Helmut
dc.contributor.authorHentschel, Joachim
dc.contributor.authorKawazoe, Urara
dc.contributor.authorFang, Jianmin
dc.contributor.authorMoreno, Silvia N. J.
dc.date.accessioned2021-09-24T11:23:40Z
dc.date.available2021-09-24T11:23:40Z
dc.date.issued2008-01eng
dc.description.abstractAcidocalcisomes are acidic calcium stores found in diverse organisms, being conserved from bacteria to man. They posses an acidic matrix that contains several cations bound to phosphates, mainly present in the form of short and long polyphosphate chains. Their matrix is acidified through the action of proton pumps such as a vacuolar proton ATPase and a vacuolar proton pyrophosphatase. The calcium uptake occurs through a Ca2+/H+ counter transporting ATPase located in the membrane of the organelle. Acidocalcisomes have been identified in a variety of microorganisms, including Apicomplexan parasites such as Plasmodium and Eimeria species, and in Toxoplasma gondii. In this paper, we review the structural, biochemical and physiological aspects of acidocalcisomes in Apicomplexan parasites and discuss their functional roles in the maintenance of intracellular ion homeostasis.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1016/j.exppara.2007.07.009eng
dc.identifier.pmid17761167eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/55022
dc.language.isoengeng
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dc.subjectToxoplasma gondii, Plasmodium falciparum, Eimeria acervulina, Apicomplexan, Acidocalcisomeseng
dc.subject.ddc570eng
dc.titleAcidocalcisomes in Apicomplexan parasiteseng
dc.typeJOURNAL_ARTICLEeng
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  title={Acidocalcisomes in Apicomplexan parasites},
  number={1},
  volume={118},
  issn={0014-4894},
  journal={Experimental Parasitology},
  pages={2--9},
  author={Miranda, Kildare and de Souza, Wanderley and Plattner, Helmut and Hentschel, Joachim and Kawazoe, Urara and Fang, Jianmin and Moreno, Silvia N. J.}
}
kops.citation.iso690MIRANDA, Kildare, Wanderley DE SOUZA, Helmut PLATTNER, Joachim HENTSCHEL, Urara KAWAZOE, Jianmin FANG, Silvia N. J. MORENO, 2008. Acidocalcisomes in Apicomplexan parasites. In: Experimental Parasitology. Elsevier. 2008, 118(1), pp. 2-9. ISSN 0014-4894. eISSN 1090-2449. Available under: doi: 10.1016/j.exppara.2007.07.009deu
kops.citation.iso690MIRANDA, Kildare, Wanderley DE SOUZA, Helmut PLATTNER, Joachim HENTSCHEL, Urara KAWAZOE, Jianmin FANG, Silvia N. J. MORENO, 2008. Acidocalcisomes in Apicomplexan parasites. In: Experimental Parasitology. Elsevier. 2008, 118(1), pp. 2-9. ISSN 0014-4894. eISSN 1090-2449. Available under: doi: 10.1016/j.exppara.2007.07.009eng
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kops.sourcefield.plainExperimental Parasitology. Elsevier. 2008, 118(1), pp. 2-9. ISSN 0014-4894. eISSN 1090-2449. Available under: doi: 10.1016/j.exppara.2007.07.009eng
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